J
Joseph C. Corbo
Researcher at Washington University in St. Louis
Publications - 94
Citations - 8604
Joseph C. Corbo is an academic researcher from Washington University in St. Louis. The author has contributed to research in topics: Enhancer & Gene. The author has an hindex of 38, co-authored 91 publications receiving 7676 citations. Previous affiliations of Joseph C. Corbo include Brigham and Women's Hospital & Stanford University.
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Journal ArticleDOI
Characterization of an immunodeficiency mutant in Drosophila
Joseph C. Corbo,Michael Levine +1 more
TL;DR: Survival assays indicate a positive correlation between the induction of these genes, particularly diptericin, and resistance to bacterial infection, which is consistent with the notion that insect anti-microbial peptides work synergistically by binding distinct targets within infecting pathogens.
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A non-coding region near Follistatin controls head colour polymorphism in the Gouldian finch.
Matthew B. Toomey,Cristiana I. Marques,Pedro Andrade,Pedro Araújo,Pedro Araújo,Stephen J. Sabatino,Małgorzata Anna Gazda,Sandra Afonso,Ricardo Lopes,Joseph C. Corbo,Miguel Carneiro +10 more
TL;DR: The genetic basis of red and black head colour in the Gouldian finch (Erythrura gouldiae), a classic polymorphic system in which naturally occurring colour morphs also display differences in aggressivity and reproductive success, is investigated.
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Optics of cone photoreceptors in the chicken (Gallus gallus domesticus).
David Wilby,Matthew B. Toomey,Peter Olsson,Rikard Frederiksen,M. Carter Cornwall,Ruth Oulton,Almut Kelber,Joseph C. Corbo,Nicholas W. Roberts +8 more
TL;DR: It is found that pigmented oil droplets primarily function as spectral filters, not light collection devices, although the mitochondrial ellipsoid improves optical coupling between the inner segment and oil droplet.
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Thyroid hormone receptors mediate two distinct mechanisms of long-wavelength vision.
Leo Volkov,Jeong Sook Kim-Han,Lauren M. Saunders,Deepak Poria,Andrew E. O. Hughes,Vladimir J. Kefalov,David M. Parichy,Joseph C. Corbo +7 more
TL;DR: It is shown that all three zebrafish thyroid hormone nuclear receptors play a role in mediating induction of cyp27c1 expression in response to thyroid hormone and that mutations in thyroid hormone receptor β result in an absence of red cones and the transfating of red cone precursors into UV cones and horizontal cells in zebra fish.
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Quantitative fine-tuning of photoreceptor cis -regulatory elements through affinity modulation of transcription factor binding sites
TL;DR: The relative binding affinity of all single-nucleotide variants of the consensus binding site of the mammalian photoreceptor transcription factor, Crx is determined and it is shown that it is possible to accurately predict the relativebinding affinity of Crx for all possible 8 bp sequences.