J
Jsm Peiris
Researcher at University of Hong Kong
Publications - 46
Citations - 6383
Jsm Peiris is an academic researcher from University of Hong Kong. The author has contributed to research in topics: Virus & Human mortality from H5N1. The author has an hindex of 15, co-authored 46 publications receiving 5999 citations. Previous affiliations of Jsm Peiris include University of Oxford.
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Journal ArticleDOI
Coronavirus as a possible cause of severe acute respiratory syndrome
Jsm Peiris,Sik To Lai,Llm Poon,Yi Guan,Lyc Yam,Wilina Lim,John M. Nicholls,Wks Yee,WW Yan,MT Cheung,V. C. C. Cheng,KH Chan,Dnc Tsang,R Yung,Ting Kin Ng,KY Yuen +15 more
TL;DR: Serological and molecular tests specific for the virus permitted a definitive laboratory diagnosis to be made and allowed further investigation to define whether other cofactors play a part in disease progression.
Journal ArticleDOI
Severe acute respiratory syndrome
TL;DR: The concerted and coordinated response that contained SARS is a triumph for global public health and provides a new paradigm for the detection and control of future emerging infectious disease threats.
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Induction of proinflammatory cytokines in human macrophages by influenza A (H5N1) viruses: a mechanism for the unusual severity of human disease?
Chung Y. Cheung,Leo L.M. Poon,A S Lau,Winsie Luk,Yu-Lung Lau,Kennedy F. Shortridge,Stephen B. Gordon,Yi Guan,Jsm Peiris +8 more
TL;DR: The H5N1/97 viruses induced much higher gene transcription of proinflammatory cytokines than did H3N2 or H1N1 viruses, particularly TNF alpha and interferon beta, which may contribute to the unusual severity of human H 5N1 disease.
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Re-emergence of fatal human influenza A subtype H5N1 disease
Jsm Peiris,W C Yu,C W Leung,CY Cheung,Wai F. Ng,John M. Nicholls,Ting Kin Ng,KH Chan,Sik To Lai,W L Lim,Kwok-Yung Yuen,Yi Guan +11 more
TL;DR: Findings suggest that cytokine dysfunction contributes to the pathogenesis of H5N1 disease and development of vaccines against influenza A (H5N 1) virus should be made a priority.
Journal ArticleDOI
Antibody-mediated enhancement of Flavivirus replication in macrophage-like cell lines
Jsm Peiris,James S. Porterfield +1 more
TL;DR: The phenomenon of antibody-dependent enhancement of viral replication is not unique to dengue virus, and may have far wider relevance in other viral infections.