J
Juan Pedro Laclette
Researcher at National Autonomous University of Mexico
Publications - 114
Citations - 4033
Juan Pedro Laclette is an academic researcher from National Autonomous University of Mexico. The author has contributed to research in topics: Taenia solium & Entamoeba histolytica. The author has an hindex of 29, co-authored 108 publications receiving 3654 citations. Previous affiliations of Juan Pedro Laclette include Harvard University.
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Journal ArticleDOI
The genomes of four tapeworm species reveal adaptations to parasitism
Isheng J. Tsai,Magdalena Zarowiecki,Nancy Holroyd,Alejandro Garciarrubio,Alejandro Sanchez-Flores,Karen Brooks,Alan Tracey,Raúl J. Bobes,Gladis Fragoso,Edda Sciutto,Martin Aslett,Helen Beasley,Hayley M. Bennett,Jianping Cai,Federico Camicia,Richard Clark,Marcela Alejandra Cucher,Nishadi De Silva,Tim A. Day,Peter Deplazes,Karel Estrada,Cecilia Fernández,Peter W. H. Holland,Junling Hou,Songnian Hu,Thomas Huckvale,Stacy S. Hung,Laura Kamenetzky,Jacqueline A. Keane,Ferenc Kiss,Uriel Koziol,Olivia Lambert,Kan Liu,Xuenong Luo,Yingfeng Luo,Natalia Macchiaroli,Sarah Nichol,Jordi Paps,John Parkinson,Natasha Pouchkina-Stantcheva,Nick Riddiford,Mara Cecilia Rosenzvit,Gustavo Salinas,James D. Wasmuth,Mostafa Zamanian,Yadong Zheng,Xuepeng Cai,Xavier Soberón,Peter D. Olson,Juan Pedro Laclette,Klaus Brehm,Matthew Berriman +51 more
TL;DR: An analysis of tapeworm genome sequences using the human-infective species Echinococcus multilocularis, E. granulosus, Taenia solium and the laboratory model Hymenolepis microstoma offers insights into the evolution of parasitism and identifies new potential drug targets.
Journal ArticleDOI
Biocompatibility and toxicological studies of carbon nanotubes doped with nitrogen.
Julio Cesar Carrero-Sánchez,Ana Laura Elías,Mancilla R,Arrellín G,Humberto Terrones,Juan Pedro Laclette,Mauricio Terrones +6 more
TL;DR: It is believed that CNx nanotubes are less harmful than MWNTs or SWNTs and might be more advantageous for bioapplications and some other routes of administration did not induce signs of distress or tissue changes on any treated mouse.
Journal ArticleDOI
Taenia solium disease in humans and pigs: an ancient parasitosis disease rooted in developing countries and emerging as a major health problem of global dimensions
Edda Sciutto,Gladis Fragoso,Agnès Fleury,Juan Pedro Laclette,Julio Sotelo,Aline S. de Aluja,Laura Rosas Vargas,Carlos Larralde +7 more
TL;DR: Current knowledge on human and porcine cysticercosis caused by Taenia solium is reviewed and current trends in research on its natural history, epidemiology, immunopathology, diagnosis, treatment and prevention are highlighted.
Journal Article
Paramyosin inhibits complement C1.
Juan Pedro Laclette,Charles B. Shoemaker,Dania Richter,Lourdes Arcos,Nelly Panté,C Cohen,D Bing,Anne Nicholson-Weller +7 more
TL;DR: The results suggest that paramyosins of helminthic parasites may have a role as modulators of the host immune response through C inhibition at C1 throughParamyosin inhibition is directed at the initiation of the classical pathway.
Journal ArticleDOI
The PE-PGRS glycine-rich proteins of Mycobacterium tuberculosis: a new family of fibronectin-binding proteins?
Clara Espitia,Juan Pedro Laclette,Mariana Mondragón-Palomino,Angelica Amador,Jaime Campuzano,Anke Martens,Mahavir Singh,Raúl Cicero,Ying Zhang,C Moreno +9 more
TL;DR: A clone was isolated by screening of a cosmid library of Mycobacterium tuberculosis with an oligonucleotide designed from the N-terminal sequence of a previously reported proline-rich protein, suggesting that at least this member of the PE-PGRS is expressed in tuberculosis infection.