J
Judith K. Christman
Researcher at Icahn School of Medicine at Mount Sinai
Publications - 16
Citations - 442
Judith K. Christman is an academic researcher from Icahn School of Medicine at Mount Sinai. The author has contributed to research in topics: Hepatitis B virus & Cellular differentiation. The author has an hindex of 11, co-authored 16 publications receiving 438 citations. Previous affiliations of Judith K. Christman include City University of New York.
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Journal ArticleDOI
Correlation between hypomethylation of DNA and expression of globin genes in Friend erythroleukemia cells.
TL;DR: The degree of hypomethylation of DNA and tRNA from FL cells induced to differentiate with dimethylsulfoxide and butyrate, and DNA isolated from cells exposed to any of the three inducers, suggest that methylation ofDNA may play a role in the regulation of gene expression.
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Effect of sodium butyrate on lymphocyte activation
TL;DR: Evidence is presented that butyrate does not interfere with the binding of mitogens, that it does not inhibit a number of the “early” reactions involved in activation, and that itdoes not affect ongoing DNA synthesis for an extended period of time.
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Effect of elevated potassium level and amino acid deprivation on polysome distribution and rate of protein synthesis in L cells
TL;DR: Evidence is presented to confirm the hypothesis that all of the components of the protein synthesizing system retain their functional integrity and that even under the most stringent conditions tested, peptide chain initiation is the rate limiting event when L-cell protein synthesis is inhibited.
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Long-term culture and passage of human fetal liver cells that synthesize albumin
M A Sells,Jonathon Chernoff,Arturo Cerda,Charles Bowers,David A. Shafritz,Nathan Kase,Judith K. Christman,George Acs +7 more
TL;DR: Long-term cultures of hepatocytes were established from livers of human fetuses obtained by abortion at 18 to 23 wk of gestation, and retained an epithelioid morphology and continued to synthesize and secrete albumin.
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Co-cultivation of tumorigenic mouse melanoma cells with cells of a non-tumorigenic subclone inhibits plasminogen activator expression by the melanoma cells.
David Kyner,Judith K. Christman,George Acs,Selma Silagi,Elizabeth W. Newcomb,Samuel C. Silverstein +5 more
TL;DR: Close contact between cells of the two lines is shown to be essential for suppression of plasminogen activation.