Julia G. Gorey

TL;DR: It is suggested that the VNTR polymorphism of the DAT gene effects translation of theDAT protein, which may explain a variety of clinical associations that have been reported with this polymorphism.

TL;DR: The hypothesis of serotonergic dysfunction in alcoholism and in withdrawal-emergent depressive symptoms is supported, which was significantly correlated with lifetime alcohol consumption and with ratings of depression and anxiety during withdrawal.

TL;DR: Within monozygotic twins discordant for Tourette syndrome severity, differences in D2 dopamine receptor binding in the head of the caudate nucleus predicted differences in phenotypic severity (r = 0.99); this relation was not observed in putamen, suggesting a spectrum of neuropsychiatric disorders that involve associative striatal circuitry.

TL;DR: Results indicate a reduction in muscarinic acetylcholine receptor availability in vivo in unmedicated patients with schizophrenia, confirming results from postmortem studies and adding further evidence that the muscaric system is involved in the pathophysiology of schizophrenia.

TL;DR: In adult nonhuman primates who underwent early developmental stress, variables indicating a low serotonin turnover rate were associated with behavior patterns similar to those predisposing to early-onset alcoholism among humans.