J
Julie P. Goff
Researcher at University of Pittsburgh
Publications - 64
Citations - 5803
Julie P. Goff is an academic researcher from University of Pittsburgh. The author has contributed to research in topics: Bone marrow & Stromal cell. The author has an hindex of 25, co-authored 61 publications receiving 5466 citations. Previous affiliations of Julie P. Goff include National Institutes of Health.
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Journal ArticleDOI
Bone marrow as a potential source of hepatic oval cells.
Bryon E. Petersen,W. C. Bowen,K. D. Patrene,Wendy M. Mars,A. K. Sullivan,N. Murase,S. S. Boggs,Joel S. Greenberger,Julie P. Goff +8 more
TL;DR: A stem cell associated with the bone marrow has epithelial cell lineage capability and a proportion of the regenerated hepatic cells were shown to be donor-derived.
Journal ArticleDOI
Age‐related intrinsic changes in human bone‐marrow‐derived mesenchymal stem cells and their differentiation to osteoblasts
Shuanhu Zhou,Joel S. Greenberger,Michael W. Epperly,Julie P. Goff,Carolyn Adler,Meryl S. LeBoff,Julie Glowacki +6 more
TL;DR: There is an age‐dependent decrease in proliferation and osteoblast differentiation, and an increase in senescence‐associated β‐galactosidase‐positive cells and apoptosis in hMSCs, which supports the view that there are intrinsic alterations in human MSCs with aging that may contribute to the process of skeletal aging in humans.
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Characterization of novel stem cell factor responsive human mast cell lines LAD 1 and 2 established from a patient with mast cell sarcoma/leukemia; activation following aggregation of FcεRI or FcγRI
Arnold S. Kirshenbaum,Cem Akin,Yalin Wu,Menachem Rottem,Julie P. Goff,Michael A. Beaven,V.Koneti Rao,Dean D. Metcalfe +7 more
TL;DR: Two novel stem cell factor (SCF) dependent human mast cell lines were established from bone marrow aspirates from a patient with mast cell sarcoma/leukemia, offering an unparalleled circumstance to examine the biology of human mast cells.
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Demonstration that human mast cells arise from a progenitor cell population that is CD34(+), c-kit(+), and expresses aminopeptidase N (CD13).
Arnold S. Kirshenbaum,Julie P. Goff,Julie P. Goff,Tekli Semere,Tekli Semere,Barbara A. Foster,Barbara A. Foster,Linda M. Scott,Linda M. Scott,D.D. Metcalfe,D.D. Metcalfe +10 more
TL;DR: Human mast cells and a population of monocytes arise from precursor cells that express CD34, c-kit, and CD13; and within which, are mast cell, monocyte, and mast/monocyte (bipotential) precursors.
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Hepatic oval cells express the hematopoietic stem cell marker Thy-1 in the rat
TL;DR: It is reported herein that HOC express high levels of Thy‐1, a cell surface marker used in conjunction with CD34 and lineage‐specific markers to identify hematopoietic stem cells, and a highly enriched population was obtained.