J
Julien Gaillard
Researcher at François Rabelais University
Publications - 27
Citations - 1417
Julien Gaillard is an academic researcher from François Rabelais University. The author has contributed to research in topics: Mesenchymal stem cell & Stromal cell. The author has an hindex of 14, co-authored 24 publications receiving 1234 citations. Previous affiliations of Julien Gaillard include Centre national de la recherche scientifique & French Institute of Health and Medical Research.
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Clinical-grade production of human mesenchymal stromal cells: occurrence of aneuploidy without transformation
Karin Tarte,Julien Gaillard,Jean-Jacques Lataillade,Loic Fouillard,Martine Becker,Hossein Mossafa,Andrei Tchirkov,Hélène Rouard,Catherine Henry,Marie Splingard,Joelle Dulong,Delphine Monnier,Patrick Gourmelon,Norbert-Claude Gorin,Luc Sensebé +14 more
TL;DR: Investigation of immunologic and genetic features of MSCs expanded with fetal calf serum and fibroblast growth factor or with platelet lysate in 4 cell-therapy facilities during 2 multicenter clinical trials found moderate expression of human leukocyte antigen-DR without alteration of their low immunogenicity or their immunomodulatory capacity.
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The Human Nose Harbors a Niche of Olfactory Ectomesenchymal Stem Cells Displaying Neurogenic and Osteogenic Properties
Bruno Delorme,Emmanuel Nivet,Julien Gaillard,Thomas Häupl,Jochen Ringe,Arnaud Deveze,Jacques Magnan,Jérôme Sohier,Michel Khrestchatisky,François S. Roman,Pierre Charbord,Luc Sensebé,Pierre Layrolle,Francois Feron +13 more
TL;DR: It is reported that when compared to bone marrow stem cells, olfactory stem cells display a high proliferation rate; a propensity to differentiate into osseous cells; and a disinclination to give rise to chondrocytes and adipocytes.
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Specific Lineage‐Priming of Bone Marrow Mesenchymal Stem Cells Provides the Molecular Framework for Their Plasticity
Bruno Delorme,Jochen Ringe,Charalampos Pontikoglou,Julien Gaillard,Alain Langonné,Luc Sensebé,Danièle Noël,Christian Jorgensen,Thomas Häupl,Pierre Charbord +9 more
TL;DR: It is shown that proliferating primary layers and clones of BM MSCs have precise priming to the osteoblastic (O), chondrocytic (C), adipocytic (A), and the vascular smooth muscle (V) lineages, but not to skeletal muscle, cardiac muscle, hematopoietic, hepatocytic, or neural lineages.
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IFITM proteins are incorporated onto HIV-1 virion particles and negatively imprint their infectivity
Kevin Tartour,Romain Appourchaux,Julien Gaillard,Xuan-Nhi Nguyen,Stéphanie Durand,Jocelyn Turpin,Elodie Beaumont,Emmanuelle Roch,Gregory Berger,Renaud Mahieux,Denys Brand,Philippe Roingeard,Andrea Cimarelli +12 more
TL;DR: The results indicate that IFITMs can target HIV at two distinct moments of its life cycle, in target cells as well as in virus-producing cells, and raise the possibility thatIFITMs could similarly affect distinct steps of the life cycle of a number of other viruses.
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Sequential biogenesis of host cell membrane rearrangements induced by hepatitis C virus infection
Pauline Ferraris,Elodie Beaumont,Rustem Uzbekov,Denys Brand,Julien Gaillard,Emmanuelle Blanchard,Philippe Roingeard +6 more
TL;DR: The main ultrastructural change observed early in infection was the formation of a network of CVs surrounding the lipid droplets, and later stages in the infectious cycle were characterized by a large increase in the number of DMVs, which may be derived from the CVs.