J
Jun Ishikawa
Researcher at Osaka University
Publications - 61
Citations - 4490
Jun Ishikawa is an academic researcher from Osaka University. The author has contributed to research in topics: Haematopoiesis & Bone marrow. The author has an hindex of 28, co-authored 61 publications receiving 4335 citations. Previous affiliations of Jun Ishikawa include University of California, Irvine.
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Journal ArticleDOI
Adiponectin, a new member of the family of soluble defense collagens, negatively regulates the growth of myelomonocytic progenitors and the functions of macrophages
Takafumi Yokota,Kenji Oritani,Isao Takahashi,Jun Ishikawa,Akifumi Matsuyama,Noriyuki Ouchi,Shinji Kihara,Tohru Funahashi,Andrea J. Tenner,Yoshiaki Tomiyama,Yuji Matsuzawa +10 more
TL;DR: The results suggest that adiponectin is an important negative regulator in hematopoiesis and immune systems and raise the possibility that it may be involved in ending inflammatory responses through its inhibitory functions.
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Expression and functional role of the proto-oncogene c-kit in acute myeloblastic leukemia cells
Hirokazu Ikeda,Yuzuru Kanakura,Toshiharu Tamaki,Akira Kuriu,Hitoshi Kitayama,Jun Ishikawa,Yoshio Kanayama,Takeshi Yonezawa,Seiichiro Tarui,James D. Griffin +9 more
TL;DR: Results indicate that c-kit proto-oncogene is expressed in most cases of AML and is functional in terms of supporting proliferation.
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Molecular cloning and chromosomal mapping of a bone marrow stromal cell surface gene, BST2, that may be involved in pre-B-cell growth.
Jun Ishikawa,Tsuneyasu Kaisho,Hitoshi Tomizawa,Byung O. Lee,Yoshiko Kobune,Johji Inazawa,Kenji Oritani,Motoyuki Itoh,Takahiro Ochi,Katsuhiko Ishihara,Toshio Hirano +10 more
TL;DR: BST-2 surface expression on fibroblast cell lines facilitated the stromal cell-dependent growth of a murine bone marrow-derived pre-B-cell line, DW34, and the results suggest that BST-2 may be involved in pre- B-cell growth.
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BST-1, a surface molecule of bone marrow stromal cell lines that facilitates pre-B-cell growth.
Tsuneyasu Kaisho,Jun Ishikawa,Kenji Oritani,Johji Inazawa,Hitoshi Tomizawa,Osamu Muraoka,Takahiro Ochi,Toshio Hirano +7 more
TL;DR: BST-1 expression was enhanced in rheumatoid arthritis patient-derived bone marrow stromal cell lines that were previously shown to have an enhanced ability to support the growth of a pre-B-cell line as compared with stromAL cell lines derived from healthy donors.
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Thrombopoietin-induced differentiation of a human megakaryoblastic leukemia cell line, CMK, involves transcriptional activation of p21(WAF1/Cip1) by STAT5.
Itaru Matsumura,Jun Ishikawa,Koichi Nakajima,Kenji Oritani,Yoshiaki Tomiyama,Jun-ichiro Miyagawa,Takashi Kato,Hiroshi Miyazaki,Yuji Matsuzawa,Yuzuru Kanakura +9 more
TL;DR: In this paper, a human megakaryoblastic leukemia cell line, CMK, was transfected with the p21, p27, or p16 gene, together with a marker gene, beta-galactosidase, and were cultured with medium alone for 5 days.