Junhua Li

TL;DR: It is reported that variation of a single amino acid residue in the innate immune sensor cGAS determines species-specific inactivation by HSV-1, and a single asparagine in human and mouse cG AS that is not conserved in many non-human primates is identified.

TL;DR: This work summarizes recent studies concerning viral manipulation of the NF-κB signaling pathway downstream of pattern recognition receptors and indicates that signal transduction mediated by pattern Recognition receptors is a research frontier for both infectious disease and innate immunology.

TL;DR: Here, studies on protein deamidation in innate immune signaling are reviewed and several imminent questions concerning the roles of protein deAmidation in infection and immunity are presented.

TL;DR: The aim of this study is to characterize the role of β‐catenin in inhibiting RIG‐I‐like receptor (RLR)‐mediated IFN‐β signalling in colorectal cancer.

TL;DR: An unexpected function of a metabolic enzyme is uncovered in restricting viral replication and a key role of deamidation in regulating protein nuclear import is revealed in regulating gamma herpesviruses.