T
Ting Liu
Researcher at Chinese Academy of Sciences
Publications - 10
Citations - 341
Ting Liu is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: Cyclin-dependent kinase complex & Cyclin A. The author has an hindex of 7, co-authored 10 publications receiving 243 citations. Previous affiliations of Ting Liu include University of Southern California & Wuhan University.
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Journal ArticleDOI
Species-Specific Deamidation of cGAS by Herpes Simplex Virus UL37 Protein Facilitates Viral Replication.
Junjie Zhang,Jun Zhao,Simin Xu,Junhua Li,Shanping He,Yi Zeng,Linshen Xie,Na Xie,Ting Liu,Katie Lee,Gil Ju Seo,Lin Chen,Alex C. Stabell,Zanxian Xia,Sara L. Sawyer,Jae U. Jung,Canhua Huang,Pinghui Feng +17 more
TL;DR: It is reported that variation of a single amino acid residue in the innate immune sensor cGAS determines species-specific inactivation by HSV-1, and a single asparagine in human and mouse cG AS that is not conserved in many non-human primates is identified.
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DNA-PK deficiency potentiates cGAS-mediated antiviral innate immunity.
Xiaona Sun,Ting Liu,Jun Zhao,Hansong Xia,Hansong Xia,Jun Xie,Yu Guo,Li Zhong,Mi Li,Qing Yang,Cheng Peng,Isabelle Rouvet,Alexandre Belot,Hong-Bing Shu,Pinghui Feng,Junjie Zhang +15 more
TL;DR: A rational explanation for the autoimmunity of patients with missense mutations of PRKDC is provided, and it is suggested that cGAS-mediated immune signaling is a potential target for therapeutic interventions.
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Phosphorylation of MCM3 Protein by Cyclin E/Cyclin-dependent Kinase 2 (Cdk2) Regulates Its Function in Cell Cycle*
TL;DR: The data reveal that the phosphorylation of MCM3 contributes to its function in controlling the S phase checkpoint of cell cycle in addition to the regulation of formation of the MCM2–7 complex.
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Phosphorylation of Minichromosome Maintenance Protein 7 (MCM7) by Cyclin/Cyclin-dependent Kinase Affects Its Function in Cell Cycle Regulation
TL;DR: The data suggest that the phosphorylation of MCM7 on Ser-121 by cyclin/Cdks is involved in preventing DNA rereplication as well as in regulation of the mitotic exit.