J
Junpei Wang
Researcher at Peking University
Publications - 44
Citations - 963
Junpei Wang is an academic researcher from Peking University. The author has contributed to research in topics: Medicine & Lipid metabolism. The author has an hindex of 10, co-authored 38 publications receiving 552 citations. Previous affiliations of Junpei Wang include Peking Union Medical College.
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Journal ArticleDOI
Long Non-Coding RNA in the Pathogenesis of Cancers.
TL;DR: The latest findings regarding the roles and mechanisms of some important lncRNAs in the pathogenesis of certain malignant cancers, including lung, breast, liver, and colorectal cancers, as well as hematological malignancies and neuroblastoma are discussed.
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Long Noncoding RNA lncSHGL Recruits hnRNPA1 to Suppress Hepatic Gluconeogenesis and Lipogenesis
Junpei Wang,Weili Yang,Zhenzhen Chen,Ji Chen,Yuhong Meng,Biaoqi Feng,Libo Sun,Lin Dou,Jian Li,Qinghua Cui,Jichun Yang +10 more
TL;DR: Acting the lncSHGL/hnRNPA1 axis represents a potential strategy for the treatment of type 2 diabetes and steatosis and is a novel insulin-independent suppressor of hepatic gluconeogenesis and lipogenesis.
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NFE2 Induces miR-423-5p to Promote Gluconeogenesis and Hyperglycemia by Repressing the Hepatic FAM3A-ATP-Akt Pathway.
Weili Yang,Junpei Wang,Zhenzhen Chen,Ji Chen,Yuhong Meng,Li-Ming Chen,Yongsheng Chang,Bin Geng,Libo Sun,Lin Dou,Jian Li,Youfei Guan,Qinghua Cui,Jichun Yang +13 more
TL;DR: Under the obese condition, activation of the hepatic NFE2/miR-423-5p axis plays important roles in the progression of type 2 diabetes and NAFLD by repressing the FAM3A-ATP-Akt signaling pathway.
Journal ArticleDOI
A bioinformatics method for predicting long noncoding RNAs associated with vascular disease
JianWei Li,JianWei Li,Cheng Gao,YuChen Wang,YuChen Wang,Wei Ma,Jian Tu,Junpei Wang,Zhenzhen Chen,Wei Kong,Qinghua Cui +10 more
TL;DR: The presented bioinformatics method and the predicted vascular disease associated lnc RNAs together may provide helps for not only better understanding of the roles of lncRNAs in vascular disease but also the identification of novel molecules for the diagnosis and therapy of vascular disease.
Journal ArticleDOI
FAM3 gene family: a promising therapeutical target for NAFLD and type 2 diabetes
TL;DR: The latest research progress on the roles and mechanisms of FAM3A, FAM3B and FAM3C in the regulation of hepatic glucose and lipid metabolism are discussed.