Qinghua Cui

TL;DR: A novel causal role of aberrant gut microbiota in contributing to the pathogenesis of hypertension is described and the significance of early intervention for pre-hypertension was emphasized.

TL;DR: The Human microRNA Disease Database (HMDD) v2.0 update presented several novel options for users to facilitate exploration of the data in the database, and presented more data that were generated based on concepts derived from the miRNA–disease association data, including disease spectrum width of miRNAs and miRNA spectrumwidth of human diseases.

TL;DR: It is uncovered that microRNAs associated with the same disease tend to emerge as predefined microRNA groups, which can not only provide help in understanding the associations between microRNAAs and human diseases but also suggest a new way to identify novel disease-associated micro RNAs.

TL;DR: The LncRNADisease database is described, which collected and curated approximately 480 entries of experimentally supported lncRNA–disease associations, including 166 diseases, and developed a bioinformatic method to predict novel lnc RNA–dISEase associations.

TL;DR: A method to infer the pairwise functional similarity and functional network for human miRNAs based on the structures of their disease relationships and can be easily extended to other species when sufficient miRNA-associated disease data are available for specific species.