K
Kaige Ma
Researcher at Huazhong University of Science and Technology
Publications - 29
Citations - 793
Kaige Ma is an academic researcher from Huazhong University of Science and Technology. The author has contributed to research in topics: Apoptosis & Viability assay. The author has an hindex of 12, co-authored 29 publications receiving 469 citations.
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Journal ArticleDOI
Autophagy is activated in compression-induced cell degeneration and is mediated by reactive oxygen species in nucleus pulposus cells exposed to compression.
Kaige Ma,Zengwu Shao,Shuhua Yang,Jianbo Wang,Baichuan Wang,Li-ming Xiong,Qiang Wu,Songfeng Chen +7 more
TL;DR: Autophagy and apoptosis were interconnected and coordinated in rat NP cells exposed to compression stimuli, and compression-induced autophagy was closely related to intracellular ROS production.
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RIPK1/RIPK3/MLKL-mediated necroptosis contributes to compression-induced rat nucleus pulposus cells death
TL;DR: RIPK1/RIPK3/MLKL-mediated necroptosis may play an important role in NP cells death induced by continuous mechanical stress, and treatment strategies which aim to regulate necroPTosis may prove beneficial, by both reducingNP cells death and slowing IVD degeneration.
Journal ArticleDOI
Mechanisms of endogenous repair failure during intervertebral disc degeneration
TL;DR: The current research situation and progress of the mechanisms through which IVD stem/progenitor cells failed to repair IVD tissues during IVD degeneration are reviewed to provide an innovative research direction for endogenous repair and a new potential treatment strategy for IVd degeneration.
Journal ArticleDOI
TGF-β signaling in intervertebral disc health and disease.
TL;DR: Investigation of the changing role of TGF-β signaling in IVD at different pathophysiological stages and its specific molecular mechanisms are needed will contribute to safe and effective TGF -β signaling-based treatments for IVD degeneration.
Journal ArticleDOI
Intervertebral Disc-Derived Stem/Progenitor Cells as a Promising Cell Source for Intervertebral Disc Regeneration.
Binwu Hu,Ruijun He,Kaige Ma,Zhe Wang,Min Cui,Hongzhi Hu,Saroj Rai,Saroj Rai,Baichuan Wang,Zengwu Shao +9 more
TL;DR: The authors believe that this review exclusively address the current understanding of IVDSCs and provide a novel approach for the IVD regeneration.