K
Katarzyna E. Greber
Researcher at Gdańsk Medical University
Publications - 26
Citations - 557
Katarzyna E. Greber is an academic researcher from Gdańsk Medical University. The author has contributed to research in topics: Antimicrobial & Antimicrobial peptides. The author has an hindex of 11, co-authored 24 publications receiving 391 citations.
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Journal ArticleDOI
Antimicrobial Peptides Under Clinical Trials.
TL;DR: Clinical trials steps are defined and current status of several antimicrobial peptides under clinical development are described as well as briefly depict peptide drug formulation.
Journal ArticleDOI
Self-assembly and interactions of short antimicrobial cationic lipopeptides with membrane lipids: ITC, FTIR and molecular dynamics studies.
Emilia Sikorska,Małgorzata Dawgul,Katarzyna E. Greber,Emilia Iłowska,Aneta Pogorzelska,Wojciech Kamysz +5 more
TL;DR: The self-organization and the behavior of the surfactant-like peptides in the presence of biological membrane models were studied and a unique interplay between the initial electrostatic and the subsequent hydrophobic interactions enabling the lipopeptides to interact with the lipid bilayer.
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Thermodynamics, size, and dynamics of zwitterionic dodecylphosphocholine and anionic sodium dodecyl sulfate mixed micelles
Emilia Sikorska,Dariusz Wyrzykowski,Kosma Szutkowski,Katarzyna E. Greber,Emilia A. Lubecka,Igor Zhukov,Igor Zhukov +6 more
TL;DR: In this paper, the thermodynamic properties of micellization for dodecylphosphocholine (DPC), SDS, and their mixtures were studied using isothermal titration calorimetry.
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Cationic Net Charge and Counter Ion Type as Antimicrobial Activity Determinant Factors of Short Lipopeptides.
TL;DR: The study shows that lipopeptides are more potent against Gram-positive than Gram-negative strains, and it was revealed that positive charge equals at least +2 is a necessary condition to observe significant antimicrobial activity, but only when it is balanced with a proper length of hydrophobic fatty acid chain.
Journal ArticleDOI
Lipophilicity Determination of Quaternary (Fluoro)Quinolones by Chromatographic and Theoretical Approaches.
Krzesimir Ciura,Joanna Fedorowicz,Filip Andrić,Katarzyna E. Greber,Alina Gurgielewicz,Wiesław Sawicki,Jarosław Sączewski +6 more
TL;DR: In this paper, a series of hybrid quaternary ammonium-fluoroquinolone-Safirinium derivatives have been synthesized as new dual-acting hydrophilic antibacterial agents.