K
Kathie A. Mihindukulasuriya
Researcher at Washington University in St. Louis
Publications - 39
Citations - 19573
Kathie A. Mihindukulasuriya is an academic researcher from Washington University in St. Louis. The author has contributed to research in topics: Human microbiome & Microbiome. The author has an hindex of 22, co-authored 37 publications receiving 16995 citations. Previous affiliations of Kathie A. Mihindukulasuriya include Baylor College of Medicine & University of Washington.
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Journal ArticleDOI
Identification of a Novel Coronavirus from a Beluga Whale by Using a Panviral Microarray
TL;DR: A panviral DNA microarray was used to investigate the death of a captive beluga whale in an aquatic park and revealed a novel virus distantly related to but most similar to group III coronaviruses, tentatively named coronavirus SW1.
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Metagenomic analysis of double-stranded DNA viruses in healthy adults
Kristine M. Wylie,Kathie A. Mihindukulasuriya,Yanjiao Zhou,Erica Sodergren,Gregory A. Storch,George M. Weinstock +5 more
TL;DR: This study is the first to use high-throughput DNA sequencing to describe the diversity of eukaryotic dsDNA viruses in a large cohort of normal individuals who were sampled at multiple body sites, and shows that the human virome is a complex component of the microbial flora.
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Sequence analysis of the human virome in febrile and afebrile children.
Kristine M. Wylie,Kathie A. Mihindukulasuriya,Erica Sodergren,George M. Weinstock,Gregory A. Storch +4 more
TL;DR: Data indicate that virus infection is associated with UF, and further studies are important in order to establish the range of viral pathogens associated with fever and to understand of the role of viral infection in fever.
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TREM2 activation on microglia promotes myelin debris clearance and remyelination in a model of multiple sclerosis.
Francesca Cignarella,Fabia Filipello,Fabia Filipello,Bryan Bollman,Claudia Cantoni,Alberto Locca,Robert Mikesell,Melissa Manis,Adiljan Ibrahim,Li Deng,Li Deng,Bruno A. Benitez,Carlos Cruchaga,Danilo Licastro,Kathie A. Mihindukulasuriya,Oscar Harari,Michael E. Buckland,David M. Holtzman,Arnon Rosenthal,Tina Schwabe,Ilaria Tassi,Laura Piccio,Laura Piccio +22 more
TL;DR: It is demonstrated that TREM2 was highly expressed on myelin-laden phagocytes in active demyelinating lesions in the CNS of subjects with MS, and antibody-dependent T REM2 activation on microglia increased density of oligodendrocyte precursors in areas of demYelination, as well as the formation of mature oligodendedrocytes thus enhancing remyelination and axonal integrity.
Journal ArticleDOI
Exploration of bacterial community classes in major human habitats
Yanjiao Zhou,Kathie A. Mihindukulasuriya,Hongyu Gao,Patricio S. La Rosa,Kristine M. Wylie,John Martin,Karthik Kota,William D. Shannon,Makedonka Mitreva,Erica Sodergren,Erica Sodergren,George M. Weinstock,George M. Weinstock +12 more
TL;DR: An analysis of the groupings of bacterial communities in stool, nasal, skin, vaginal and oral habitats in a healthy cohort of 236 subjects from the Human Microbiome Project strengthens the understanding of the variability and dynamics of human microbiomes.