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Kathleen R. Lamborn
Researcher at University of California, San Francisco
Publications - 268
Citations - 27324
Kathleen R. Lamborn is an academic researcher from University of California, San Francisco. The author has contributed to research in topics: Glioma & Radioimmunotherapy. The author has an hindex of 88, co-authored 268 publications receiving 25597 citations. Previous affiliations of Kathleen R. Lamborn include Stanford University & Dartmouth College.
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Journal ArticleDOI
Updated Response Assessment Criteria for High-Grade Gliomas: Response Assessment in Neuro-Oncology Working Group
Patrick Y. Wen,David R. Macdonald,David A. Reardon,Timothy F. Cloughesy,A. Gregory Sorensen,Evanthia Galanis,John DeGroot,Wolfgang Wick,Mark R. Gilbert,Andrew B. Lassman,Christina Tsien,Tom Mikkelsen,Eric T. Wong,Marc C. Chamberlain,Roger Stupp,Kathleen R. Lamborn,Michael A. Vogelbaum,Martin J. van den Bent,Susan M. Chang +18 more
TL;DR: The recognition that contrast enhancement is nonspecific and may not always be a true surrogate of tumor response and the need to account for the nonenhancing component of the tumor mandate that new criteria be developed and validated to permit accurate assessment of the efficacy of novel therapies.
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Role of Extent of Resection in the Long-Term Outcome of Low-Grade Hemispheric Gliomas
Justin S. Smith,Edward F. Chang,Kathleen R. Lamborn,Susan M. Chang,Michael D. Prados,Soonmee Cha,Tarik Tihan,Scott R. VandenBerg,Michael W. McDermott,Mitchel S. Berger +9 more
TL;DR: Improved outcome among adult patients with hemispheric LGG is predicted by greater EOR, and progression-free survival was predicted by log preoperative tumor volume and postoperative volume.
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Gene expression profiling reveals molecularly and clinically distinct subtypes of glioblastoma multiforme
Yu Liang,Maximilian Diehn,Nathan P. Watson,Andrew W. Bollen,Kenneth Aldape,M. Kelly Nicholas,Kathleen R. Lamborn,Mitchel S. Berger,David Botstein,Patrick O. Brown,Mark A. Israel +10 more
TL;DR: It is found that the gene expression patterns in paired specimens from the same GBM invariably were more closely related to each other than to any other tumor, even when the paired specimens had strikingly divergent histologies.
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Epidermal Growth Factor Receptor, Protein Kinase B/Akt, and Glioma Response to Erlotinib
Daphne A. Haas-Kogan,Michael D. Prados,Tarik Tihan,David A. Eberhard,Nannette Jelluma,Nils D. Arvold,Rachel Baumber,Kathleen R. Lamborn,Ami Kapadia,Mary Malec,Mitchel S. Berger,David Stokoe +11 more
TL;DR: Among glioma patients, those with glioblastoma multiforme tumors who have high levels of EGFR expression and low levels of phosphorylated PKB/Akt had better response to erlotinib treatment than those with low levels.
Journal ArticleDOI
Prognostic factors for survival of patients with glioblastoma: Recursive partitioning analysis
TL;DR: Subgroup analyses indicated that inclusion of adjuvant chemotherapy provides an increase in survival, although that improvement tends to be minimal for patients over age 65, for patientsover age 40 with KPS less than 80, and for those treated with brachytherapy.