K
Katsuhiko Nawa
Researcher at University of Tokushima
Publications - 14
Citations - 2153
Katsuhiko Nawa is an academic researcher from University of Tokushima. The author has contributed to research in topics: Thrombomodulin & Recombinant DNA. The author has an hindex of 10, co-authored 14 publications receiving 2111 citations.
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Journal ArticleDOI
Partial purification and characterization of hepatocyte growth factor from serum of hepatectomized rats.
TL;DR: Results suggest that hepatotropin is a new growth factor that did not stimulate DNA synthesis in cultured hepatocytes and was additive with that of insulin plus epidermal growth factor.
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Purification and subunit structure of hepatocyte growth factor from rat platelets
TL;DR: Biological and chemical properties showed that HGF was not identical with any known growth factors, including platelet‐derived growth factor (PDGF), which was found to be a beat‐ and acid‐labile protein that was inactivated by reduction with dithiothreitol.
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Multihormonal regulation of transcription of the tryptophan 2,3-dioxygenase gene in primary cultures of adult rat hepatocytes with special reference to the presence of a transcriptional protein mediating the action of glucocorticoids.
Toshikazu Nakamura,S Niimi,Katsuhiko Nawa,Chiseko Noda,Akira Ichihara,Yasuyuki Takagi,M Anai,Y Sakaki +7 more
TL;DR: Findings indicate that a short-lived transcriptional protein, which is also regulated by glucocorticoids, mediates their effect on expression of the TO gene.
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Glucocorticoid-dependent expression of the albumin gene in adult rat hepatocytes.
TL;DR: The in vitro finding that expression of the albumin gene is strictly regulated by glucocorticoid was confirmed by an in vivo experiment in adrenalectomized rats showing that the transcription decreased markedly 14 days after adrenalectomy, but was restored rapidly by administration of hydrocortisone.
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Presence and function of chondroitin-4-sulfate on recombinant human soluble thrombomodulin
Katsuhiko Nawa,Katsuichi Sakano,Hiroyuki Fujiwara,Yoshinari Sato,Norifumi Sugiyama,Toshiyuki Teruuchi,Masahiro Iwamoto,Yasumasa Marumoto +7 more
TL;DR: The authors constructed a human soluble thrombomodulin expression vector using the RSV promoter and found that RsTM beta was more effective at inhibition of thrombin clotting activity and had antithrombin III-dependent anticoagulant activity which was not possessed by rsTM alpha.