K
Kazuhide Yamamoto
Researcher at Okayama University
Publications - 482
Citations - 12159
Kazuhide Yamamoto is an academic researcher from Okayama University. The author has contributed to research in topics: Hepatocellular carcinoma & Autoimmune hepatitis. The author has an hindex of 52, co-authored 479 publications receiving 10842 citations. Previous affiliations of Kazuhide Yamamoto include Shiga University of Medical Science.
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Journal ArticleDOI
Daclatasvir plus asunaprevir for chronic HCV genotype 1b infection.
Hiromitsu Kumada,Yoshiyuki Suzuki,Kenji Ikeda,Joji Toyota,Yoshiyasu Karino,Kazuaki Chayama,Yoshiiku Kawakami,Akio Ido,Kazuhide Yamamoto,Koichi Takaguchi,Namiki Izumi,Kazuhiko Koike,Tetsuo Takehara,Norifumi Kawada,Michio Sata,Hidetaka Miyagoshi,Timothy Eley,Fiona McPhee,Andrew Damokosh,Hiroki Ishikawa,Eric Hughes +20 more
TL;DR: Interferon‐free, ribavirin‐free all‐oral therapy with daclatasvir and asunaprevir for 24 weeks is well tolerated and can achieve a high rate of SVR in patients with HCV genotype 1b who were ineligible, intolerant, or had not responded to prior interferon-based therapy.
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Multiple Hits, Including Oxidative Stress, as Pathogenesis and Treatment Target in Non-Alcoholic Steatohepatitis (NASH)
TL;DR: Targeting mitochondrial oxidative stress might be a good candidate for NASH treatment because molecular hydrogen is an effective antioxidant that reduces only cytotoxic reactive oxygen species (ROS) and several diseases associated with oxidative stress are sensitive to hydrogen.
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Genome-wide association study identifies TNFSF15 and POU2AF1 as susceptibility loci for primary biliary cirrhosis in the Japanese population.
Minoru Nakamura,Nao Nishida,Minae Kawashima,Yoshihiro Aiba,Atsushi Tanaka,Michio Yasunami,Hitomi Nakamura,Atsumasai Komori,Makoto Nakamuta,Mikio Zeniya,Etsuko Hashimoto,Hiromasa Ohira,Kazuhide Yamamoto,Morikazu Onji,Shuichi Kaneko,Masao Honda,Satoshi Yamagiwa,Kazuhiko Nakao,Takafumi Ichida,Hajime Takikawa,Masataka Seike,Takeji Umemura,Yoshiyuki Ueno,Shotaro Sakisaka,Kentaro Kikuchi,Hirotoshi Ebinuma,Noriyo Yamashiki,S. Tamura,Yasuhiko Sugawara,Akira Mori,Shintaro Yagi,Ken Shirabe,Akinobu Taketomi,Kuniaki Arai,Kyoko Monoe,Tatsuki Ichikawa,Makiko Taniai,Yasuhiro Miyake,Teru Kumagi,Masanori Abe,Kaname Yoshizawa,Satoru Joshita,Shinji Shimoda,Koichi Honda,Hiroki Takahashi,Katsuji Hirano,Yasuaki Takeyama,Kenichi Harada,Kiyoshi Migita,Masahiro Ito,Hiroshi Yatsuhashi,Nobuyoshi Fukushima,Hajime Ota,Tatsuji Komatsu,Takeo Saoshiro,Jinya Ishida,Hirotsugu Kouno,Hirotaka Kouno,Michiyasu Yagura,Masakazu Kobayashi,Toyokichi Muro,Naohiko Masaki,Keiichi Hirata,Yukio Watanabe,Yoko Nakamura,Masaaki Shimada,Noboru Hirashima,Toshiki Komeda,Kazuhiro Sugi,Michiaki Koga,Keisuke Ario,Eiichi Takesaki,Yoshihiko Maehara,Shinji Uemoto,Norihiro Kokudo,Hirohito Tsubouchi,Masashi Mizokami,Yasuni Nakanuma,Katsushi Tokunaga,Hiromi Ishibashi +79 more
TL;DR: Observations indicated the existence of ethnic differences in genetic susceptibility loci to PBC and the importance of TNF signaling and B cell differentiation for the development of PBC in individuals of European descent and Japanese individuals.
Journal ArticleDOI
The presence of large serrated polyps increases risk for colorectal cancer.
Sakiko Hiraoka,Jun Kato,Shigeatsu Fujiki,Eisuke Kaji,Tamiya Morikawa,Takatoshi Murakami,Toru Nawa,Motoaki Kuriyama,Toshio Uraoka,Nobuya Ohara,Kazuhide Yamamoto +10 more
TL;DR: The presence of large serrated polyps is a risk factor for colorectal cancer, particularly CRC of the proximal colon, and the presence of LSPs was the greatest risk factors for CRC.
Journal ArticleDOI
Detection of K-ras gene mutation by liquid biopsy in patients with pancreatic cancer.
Hideaki Kinugasa,Kazuhiro Nouso,Koji Miyahara,Yuki Morimoto,Chihiro Dohi,Koichiro Tsutsumi,Hironari Kato,Takehiro Matsubara,Hiroyuki Okada,Kazuhide Yamamoto +9 more
TL;DR: The clinical usefulness of genetic analysis for ctDNA by digital polymerase chain reaction in patients with pancreatic cancer is estimated.