K
Kazuhiro Tateda
Researcher at Toho University
Publications - 61
Citations - 3058
Kazuhiro Tateda is an academic researcher from Toho University. The author has contributed to research in topics: Pseudomonas aeruginosa & Legionella pneumophila. The author has an hindex of 27, co-authored 61 publications receiving 2838 citations. Previous affiliations of Kazuhiro Tateda include University of Tokyo.
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Journal ArticleDOI
Cytosolic recognition of flagellin by mouse macrophages restricts Legionella pneumophila infection
Ari B. Molofsky,Brenda G. Byrne,Natalie N. Whitfield,Cressida A. Madigan,Etsu T. Fuse,Kazuhiro Tateda,Michele S. Swanson +6 more
TL;DR: In this paper, the authors reported that mouse macrophages restricted Legionella pneumophila replication and initiated a proinfl ammatory program of cell death when fl agellin contaminated their cytosol.
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The Pseudomonas aeruginosa autoinducer N-3-oxododecanoyl homoserine lactone accelerates apoptosis in macrophages and neutrophils.
Kazuhiro Tateda,Yoshikazu Ishii,Manabu Horikawa,Tetsuya Matsumoto,Shinichi Miyairi,Jean-Claude Pechère,Theodore J. Standiford,Masaji Ishiguro,Keizo Yamaguchi +8 more
TL;DR: The data suggest that the quorum-sensing molecule 3-oxo-C12-HSL has critical roles in the pathogenesis of P. aeruginosa infection, not only in the induction of bacterial virulence factors but also in the modulation of host responses.
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Efficacy of Bacteriophage Therapy against Gut-Derived Sepsis Caused by Pseudomonas aeruginosa in Mice
Ryohei Watanabe,Tetsuya Matsumoto,Go Sano,Yoshikazu Ishii,Kazuhiro Tateda,Yoshinobu Sumiyama,Jumpei Uchiyama,Shingo Sakurai,Shigenobu Matsuzaki,Shosuke Imai,Keizo Yamaguchi +10 more
TL;DR: It is suggested that oral administration of phage may be effective against gut-derived sepsis caused by P. aeruginosa, and the levels of inflammatory cytokines in blood and liver were significantly lower inphage-treated mice than in phage-untreated mice.
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Azithromycin blocks neutrophil recruitment in Pseudomonas endobronchial infection
Wan C. Tsai,Michael L. Rodriguez,Katherine S. Young,Jane C. Deng,Victor J. Thannickal,Kazuhiro Tateda,Marc B. Hershenson,Theodore J. Standiford +7 more
TL;DR: It is indicated that the azithromycin treatment in vivo results in significant reduction in airway-specific inflammation, which occurs in part by inhibition of neutrophil recruitment to the lung through reduction in proinflammatory cytokine expression and inhibition ofNeutrophil migration via the extracellular signal-regulated kinase-1 and -2 signal transduction pathway.
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Efficacy of colistin combination therapy in a mouse model of pneumonia caused by multidrug-resistant Pseudomonas aeruginosa
Nobumasa Aoki,Nobumasa Aoki,Kazuhiro Tateda,Yoshiaki Kikuchi,Soichiro Kimura,Choichiroh Miyazaki,Yoshikazu Ishii,Yoshinari Tanabe,Fumitake Gejyo,Keizo Yamaguchi +9 more
TL;DR: Data suggest that colistin may be an important option for combination therapy against critical MDRP infections, especially for pneumonia especially, and not only for synergistic antibacterial activity, but also for blocking LPS.