K
Kazuo Umetsu
Researcher at Yamagata University
Publications - 177
Citations - 3797
Kazuo Umetsu is an academic researcher from Yamagata University. The author has contributed to research in topics: Population & Gene. The author has an hindex of 29, co-authored 177 publications receiving 3600 citations.
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Journal ArticleDOI
Mitochondrial Genome Variation in Eastern Asia and the Peopling of Japan
Masashi Tanaka,Vicente M. Cabrera,Ana M. González,José M. Larruga,Takeshi Takeyasu,Takeshi Takeyasu,Noriyuki Fuku,Li Jun Guo,Li Jun Guo,Raita Hirose,Yasunori Fujita,Miyuki Kurata,Ken-ichi Shinoda,Kazuo Umetsu,Yoshiji Yamada,Yoshiji Yamada,Yoshiharu Oshida,Yuzo Sato,Nobutaka Hattori,Yoshikuni Mizuno,Yasumichi Arai,Nobuyoshi Hirose,Shigeo Ohta,Osamu Ogawa,Yasushi Tanaka,Ryuzo Kawamori,Masayo Shamoto-Nagai,Wakako Maruyama,Hiroshi Shimokata,Ryota Suzuki,Hidetoshi Shimodaira +30 more
TL;DR: Population-based comparisons confirmed that present-day Japanese have their closest genetic affinity to northern Asian populations, especially to Koreans, which finding is congruent with the proposed Continental gene flow to Japan after the Yayoi period.
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Mitochondrial GTPase mitofusin 2 mutation in Charcot-Marie-Tooth neuropathy type 2A
Kazuki Kijima,Chikahiko Numakura,Hiroko Izumino,Kazuo Umetsu,Atsuo Nezu,Toshihide Shiiki,Masafumi Ogawa,Yoshito Ishizaki,Takeshi Kitamura,Yasunobu Shozawa,Kiyoshi Hayasaka +10 more
TL;DR: Researchers studied MFN2 in 81 Japanese patients with axonal or unclassified CMT and detected seven mutations in seven unrelated patients, six of them were novel and one of them was a de novo mutation.
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Two universal primer sets for species identification among vertebrates.
TL;DR: Two primer sets were designed based on the conserved regions of the 12S and 16S rRNA loci detected by the comprehensive sequence comparison among 30 mammalian whole mitochondrial genomes and successfully amplified the expected PCR products from various kinds of vertebrates.
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Neonatal hyperbilirubinemia and mutation of the bilirubin uridine diphosphate-glucuronosyltransferase gene: a common missense mutation among Japanese, Koreans and Chinese.
Kazuhiro Akaba,Toshiyuki Kimura,Ayako Sasaki,Saori Tanabe,Tohru Ikegami,Motoya Hashimoto,Hitoshi Umeda,Hiroshi Yoshida,Kazuo Umetsu,Hitoshi Chiba,Isao Yuasa,Kiyoshi Hayasaka +11 more
TL;DR: The data suggest that the high frequency of the Gly71Arg mutation of the B‐UGT gene is associated with high incidence of neonatal hyperbilirubinemia in Japanese, Korean and Chinese populations.
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The history of human populations in the Japanese Archipelago inferred from genome-wide SNP data with a special reference to the Ainu and the Ryukyuan populations
Timothy A. Jinam,Nao Nishida,Momoki Hirai,Shoji Kawamura,Hiroki Oota,Kazuo Umetsu,Ryosuke Kimura,Jun Ohashi,Atsushi Tajima,Toshimichi Yamamoto,Hideyuki Tanabe,Shuhei Mano,Yumiko Suto,Tadashi Kaname,Kenji Naritomi,Kumiko Yanagi,Norio Niikawa,Keiichi Omoto,Katsushi Tokunaga,Naruya Saitou +19 more
TL;DR: Close to one million single-nucleotide polymorphisms for the Ainu and the Ryukyuan are determined, and the dual structure model on the Japanese Archipelago populations clearly support, though the origins of the Jomon and the Yayoi people still remain to be solved.