K
Kei Yamaguchi
Researcher at National Institute of Advanced Industrial Science and Technology
Publications - 4
Citations - 410
Kei Yamaguchi is an academic researcher from National Institute of Advanced Industrial Science and Technology. The author has contributed to research in topics: Endosome & Induced pluripotent stem cell. The author has an hindex of 2, co-authored 4 publications receiving 377 citations.
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Journal ArticleDOI
Direct reprogramming of somatic cells is promoted by maternal transcription factor Glis1
Momoko Maekawa,Kei Yamaguchi,Tomonori Nakamura,Ran Shibukawa,Ikumi Kodanaka,Tomoko Ichisaka,Yoshifumi Kawamura,Hiromi Mochizuki,Naoki Goshima,Shinya Yamanaka +9 more
TL;DR: DNA microarray analyses show that Glis1 effectively promotes the direct reprogramming of somatic cells during iPSC generation, including Myc, Nanog, Lin28, Wnt, Essrb and the mesenchymal–epithelial transition.
Journal ArticleDOI
Efficient Protein Transduction Method Using Cationic Peptides and Lipids
TL;DR: This work has developed a novel protein delivery system to enhance the proton sponge effect, which results in rupture of the endosomes, by using a mixture of Wr-T transporter peptide and a commercially available cationic lipid reagent.
Journal ArticleDOI
Identification and characterization of the antigen recognized by the germ cell mAb TRA98 using a human comprehensive wet protein array.
Eriko Fukuda,Hiromitsu Tanaka,Kei Yamaguchi,Mieko Takasaka,Yoshifumi Kawamura,Hidenobu Okuda,Ayako Isotani,Masahito Ikawa,Virginia Smith Shapiro,Junji Tsuchida,Yuki Okada,Akira Tsujimura,Yasushi Miyagawa,Shinichiro Fukuhara,Yoshitaka Kawakami,Morimasa Wada,Yoshitake Nishimune,Naoki Goshima +17 more
TL;DR: In this article, a human comprehensive wet protein array was developed containing 19,446 proteins derived from human cDNAs, and it was found that the antigen recognized by mAb TRA98 is not a GCNA gene product, but nuclear factor-κB activating protein (NKAP).
Journal ArticleDOI
A Pilot Study on the Effect of Anti-Thrombopoietin Antibody on Platelet Count in Patients with Type 2 Diabetes
Takuya Fukuda,Masahide Hamaguchi,Takafumi Osaka,Yoshitaka Hashimoto,Emi Ushigome,Mai Asano,Masahiro Yamazaki,Eriko Fukuda,Kei Yamaguchi,Koji Ogawa,Naoki Goshima,Michiaki Fukui +11 more
TL;DR: This was the first report on the effect of the anti-THPO antibody on platelet count in patients with type 2 diabetes mellitus, and multivariate linear regression analyses showed a significant relationship between theAnti-TH PO antibody and platelets, after adjusting for other variables.