K
Ken Price
Publications - 5
Citations - 715
Ken Price is an academic researcher. The author has contributed to research in topics: Coreceptor activity & Receptor. The author has an hindex of 4, co-authored 4 publications receiving 700 citations.
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Journal ArticleDOI
Epitope mapping of CCR5 reveals multiple conformational states and distinct but overlapping structures involved in chemokine and coreceptor function.
Benhur Lee,Benhur Lee,Matthew Sharron,Cédric Blanpain,Benjamin J. Doranz,Jalal Vakili,Pui Setoh,Ellen L. Berg,Gao Liu,H. Robert Guy,Stewart R. Durell,Marc Parmentier,Chung Nan Chang,Ken Price,Monica Tsang,Robert W. Doms +15 more
TL;DR: The results imply that chemokines and Env bind to distinct but overlapping sites in CCR5, and suggest that the N-terminal domain of C CR5 is more important for gp120 binding while the extracellular loops are moreimportant for inducing conformational changes in Env that lead to membrane fusion and virus infection.
Journal ArticleDOI
Antigenically distinct conformations of CXCR4.
Frédéric Baribaud,Terri G. Edwards,Matthew Sharron,Anne Brelot,Nikolaus Heveker,Ken Price,Frank Mortari,Marc Alizon,Monica Tsang,Robert W. Doms +9 more
TL;DR: It is found that CXCR4 on both primary and transformed T cells as well as on primary B cells exhibited considerable conformational heterogeneity, and the fact that this important HIV-1 coreceptor exists in multiple conformations could have implications for viral entry and for the development of receptor antagonists.
Journal ArticleDOI
Expression and coreceptor activity of STRL33/Bonzo on primary peripheral blood lymphocytes.
Matthew Sharron,Stefan Pöhlmann,Ken Price,Elias Lolis,Monica Tsang,Frank Kirchhoff,Robert W. Doms,Benhur Lee +7 more
TL;DR: The expression pattern and coreceptor activity of STRL33 suggest its involvement in trafficking of tumor-infiltrating lymphocytes and indicate that STRL 33 may be a relevant coreceptor in vivo.
Journal ArticleDOI
Expression and coreceptor function of APJ for primate immunodeficiency viruses.
Bridget A. Puffer,Matthew Sharron,Christine M. Coughlan,Frédéric Baribaud,Carrie M. McManus,Benhur Lee,Jim David,Ken Price,Richard Horuk,Monica Tsang,Robert W. Doms +10 more
TL;DR: It was found that APJ could not be detected by FACS analysis on cell lines commonly used to propagate primate lentiviruses, nor was it expressed on human PBMC cultured under a variety of conditions, indicating that in some situations APJ use could render primary cell types susceptible to virus infection.
Characterization of a Viral Suppressor of RNA Silencing Encoded by CLRDV-AL
TL;DR: Agrofoglio et al. as mentioned in this paper identified the P0 protein as a suppressor of RNA silencing in Cotton Leafroll Dwarf Virus (CLRDV) infection.