K
Ken Sugimoto
Researcher at Hamamatsu University School of Medicine
Publications - 322
Citations - 9388
Ken Sugimoto is an academic researcher from Hamamatsu University School of Medicine. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 37, co-authored 281 publications receiving 6492 citations. Previous affiliations of Ken Sugimoto include Health Science University & University of California, San Francisco.
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Journal ArticleDOI
Identification of evidence suggestive of an association with peripheral arterial disease at the OSBPL10 locus by genome-wide investigation in the Japanese population.
Hiroshi Koriyama,Hironori Nakagami,Tomohiro Katsuya,Ken Sugimoto,Hidetoshi Yamashita,Yoichi Takami,Shiro Maeda,Michiaki Kubo,Atsushi Takahashi,Yusuke Nakamura,Toshio Ogihara,Hiromi Rakugi,Yasufumi Kaneda,Ryuichi Morishita +13 more
TL;DR: A two-staged genome-wide exploration in Japanese individuals identified suggestive evidence of PAD association at the OSBPL10 locus, and further replication study is warranted for verification in the Japanese population.
Journal ArticleDOI
A Polymorphism Regulates CYP4A11 Transcriptional Activity and Is Associated With Hypertension in a Japanese Population
Ken Sugimoto,Hiroshi Akasaka,Tomohiro Katsuya,Koichi Node,Tomomi Fujisawa,Izumi Shimaoka,Osamu Yasuda,Mitsuru Ohishi,Toshio Ogihara,Kazuaki Shimamoto,Hiromi Rakugi +10 more
TL;DR: A functional variant (−845A/G) of CYP4A11 that is significantly associated with hypertension and that appears to be a novel candidate for a predisposing factor for hypertension is identified.
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Telmisartan increases fatty acid oxidation in skeletal muscle through a peroxisome proliferator-activated receptor-γ dependent pathway
Ken Sugimoto,Ludmila Kazdova,Nathan Qi,Masaya Hyakukoku,Vladimír Křen,Miroslava Šimáková,Vaclav Zidek,Theodore W. Kurtz,Michal Pravenec +8 more
TL;DR: The current results are consistent with the possibility that telmisartan may increase energy expenditure and protect against dietary induced obesity and features of the metabolic syndrome at least in part by increasing muscle fatty acid oxidation through activation of peroxisome proliferator-activated receptor-γ.
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High incidence of autoimmune gastritis in patients misdiagnosed with two or more failures of H. pylori eradication
Takahisa Furuta,Satoshi Baba,Mihoko Yamade,Takahiro Uotani,Takuma Kagami,Takahiro Suzuki,Shinya Tani,Yasushi Hamaya,Moriya Iwaizumi,Satoshi Osawa,Ken Sugimoto +10 more
TL;DR: Although autoimmune gastritis is generally considered relatively rare, it frequently encounter AIG among patients at to the authors' hospital who have experienced at least two episodes of Helicobacter pylori eradication failure.
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The influence of aging on the diagnosis of primary aldosteronism
Chikako Nakama,Kei Kamide,Tatsuo Kawai,Kazuhiro Hongyo,Norihisa Ito,Miyuki Onishi,Yasushi Takeya,Koichi Yamamoto,Ken Sugimoto,Hiromi Rakugi +9 more
TL;DR: Patients who were not taking antihypertensive medications or calcium channel blockers and α blockers that underwent PRA and plasma aldosterone concentration measurements were evaluated and the influence of aging in the diagnosis of elderly subjects with PA was clarified.