K
Kenryo Furushima
Researcher at Wakayama Medical University
Publications - 7
Citations - 157
Kenryo Furushima is an academic researcher from Wakayama Medical University. The author has contributed to research in topics: Receptor tyrosine kinase & Fibroblast growth factor 23. The author has an hindex of 6, co-authored 7 publications receiving 116 citations.
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Journal ArticleDOI
Viable offspring obtained from Prm1-deficient sperm in mice
Naoki Takeda,Kazuya Yoshinaga,Kenryo Furushima,Kazufumi Takamune,Zhenghua Li,Shin Ichi Abe,Shin Aizawa,Ken Ichi Yamamura +7 more
TL;DR: The result suggests that sperm lacking Prm1 can generate offspring despite being abnormally shaped and having destabilised DNA, decondensed chromatin and a reduction in mitochondrial membrane potential, and these mice showed little derangement of expression profiles.
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Persistent fibroblast growth factor 23 signalling in the parathyroid glands for secondary hyperparathyroidism in mice with chronic kidney disease
Kazuki Kawakami,Ai Takeshita,Kenryo Furushima,Masayasu Miyajima,Ikuji Hatamura,Makoto Kuro-o,Yasuhide Furuta,Kazushige Sakaguchi +7 more
TL;DR: FGF23 is a long-term inducer of parathyroid cell proliferation and PTH secretion, and is one cause of secondary hyperparathyroidism in CKD.
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Central role of the proximal tubular αKlotho/FGF receptor complex in FGF23-regulated phosphate and vitamin D metabolism
TL;DR: The findings suggest that the primary function of FGF23 on mineral metabolism is mediated through αKlotho/FGFR co-receptors expressed in proximal tubular cells, and that the putative enzymatic function of αKLotho in the proximaltubule has a minor role in systemic mineral metabolism.
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Crosstalk of Humoral and Cell-Cell Contact-Mediated Signals in Postnatal Body Growth
Xuefeng Jing,Masayasu Miyajima,Takahiro Sawada,Qingfa Chen,Keiji Iida,Kenryo Furushima,Daiki Arai,Kazuo Chihara,Kazushige Sakaguchi +8 more
TL;DR: It is suggested that the local cell-cell contact-mediated ephrin/EphA4 signal is as important as the humoral GH signal in IGF1 synthesis and body size determination.
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EphA4 Regulates the Balance between Self-Renewal and Differentiation of Radial Glial Cells and Intermediate Neuronal Precursors in Cooperation with FGF Signaling.
Qingfa Chen,Daiki Arai,Kazuki Kawakami,Takahiro Sawada,Xuefeng Jing,Masayasu Miyajima,Syu-ichi Hirai,Kazushige Sakaguchi,Kenryo Furushima +8 more
TL;DR: The results suggest that EphA4, in cooperation with an FGF signal, contributes to the maintenance of R GC self-renewal and repression of RGC differentiation through the neuronal lineage.