N
Naoki Takeda
Researcher at Kumamoto University
Publications - 64
Citations - 7493
Naoki Takeda is an academic researcher from Kumamoto University. The author has contributed to research in topics: Gene & Somatic cell. The author has an hindex of 33, co-authored 64 publications receiving 7125 citations.
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Journal ArticleDOI
Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice
Dusko Ilic,Yasuhide Furuta,Satoshi Kanazawa,Naoki Takeda,Kenji Sobue,Norio Nakatsuji,S Nomura,Jiro Fujimoto,Masato Okada,Tadashi Yamamoto +9 more
TL;DR: Surprisingly, the number of focal adhesions was increased in FAK-deficient cells, suggesting that FAK may be involved in the turnover of focalAdhesion contacts during cell migration.
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Mouse Otx2 functions in the formation and patterning of rostral head.
TL;DR: The homo- and heterozygous mutant phenotypes suggest Otx2 functions as a gap-like gene in the rostral head where Hox code is not present, suggesting its evolutionary significance for the innovation of the neurocranium and the jaw.
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A Novel ES Cell Line, TT2, with High Germline-Differentiating Potency
Takeshi Yagi,Tomoyuki Tokunaga,Yasuhide Furuta,S. Nada,M. Yoshida,T. Tsukada,Y. Saga,Naoki Takeda,Yoji Ikawa,Shinichi Aizawa +9 more
TL;DR: TT2 cells can serve as a valuable vehicle for the production of mutant mice by segregating inside the blastomeres, localized in an inner cell mass of blastocysts, and colonized efficiently in each tissue of the pups.
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Parthenogenetic activation of oocytes in c-mos-deficient mice
Naohiro Hashimoto,Nobumoto Watanabe,Yasuhide Furuta,Hiroyuki Tamemoto,Noriyuiki Sagata,Minesuke Yokoyama,Kenji Okazaki,Mariko Nagayoshi,Naoki Takeda,Yoji Ikawa,Shinichi Aizawa +10 more
TL;DR: Results indicate that in mice Mos plays a role in the second meiotic metaphase arrest, but does not seem to be essential for the initiation of oocyte maturation, spermatogenesis or somatic cell cycle.
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Emx1 and Emx2 functions in development of dorsal telencephalon
Michio Yoshida,Yoko Suda,Isao Matsuo,Norimasa Miyamoto,Naoki Takeda,Shigeru Kuratani,Shinichi Aizawa +6 more
TL;DR: Phenotypes of newborn brains also suggest that these genes function in neurogenesis corresponding to their later expressions, and Emx2 most likely delineates the palliochoroidal boundary in the absence of Emx1 expression during early dorsal forebrain patterning.