K
Kensuke Egashira
Researcher at Kyushu University
Publications - 335
Citations - 28520
Kensuke Egashira is an academic researcher from Kyushu University. The author has contributed to research in topics: Monocyte & Inflammation. The author has an hindex of 88, co-authored 335 publications receiving 26822 citations. Previous affiliations of Kensuke Egashira include Nara Institute of Science and Technology & Ochanomizu University.
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Journal ArticleDOI
MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity
Hajime Kanda,Sanshiro Tateya,Yoshikazu Tamori,Ko Kotani,Ko Kotani,Kenichi Hiasa,Riko Kitazawa,Sohei Kitazawa,Hitoshi Miyachi,Sakan Maeda,Kensuke Egashira,Masato Kasuga +11 more
TL;DR: It is suggested that an increase in MCP-1 expression in adipose tissue contributes to the macrophage infiltration into this tissue, insulin resistance, and hepatic steatosis associated with obesity in mice.
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The importance of the hyperpolarizing mechanism increases as the vessel size decreases in endothelium-dependent relaxations in rat mesenteric circulation.
Hiroaki Shimokawa,Hiroshi Yasutake,Koji Fujii,M. Owada,Ryuichi Nakaike,Yoshihiro Fukumoto,Tsuneo Takayanagi,Tetsuhiko Nagao,Kensuke Egashira,Masatoshi Fujishima,Akira Takeshita +10 more
TL;DR: The results indicate that the importance of EDHF increases as the vessel size decreases in endothelium-dependent relaxations in the rat mesenteric circulation.
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Mitochondrial Electron Transport Complex I Is a Potential Source of Oxygen Free Radicals in the Failing Myocardium
Tomomi Ide,Hiroyuki Tsutsui,Shintaro Kinugawa,Hideo Utsumi,Dongchon Kang,Nobutaka Hattori,Koji Uchida,Ken ichi Arimura,Kensuke Egashira,Akira Takeshita +9 more
TL;DR: Direct evidence is provided for the involvement of ROS in the mitochondrial origin of HF myocytes, which might be responsible for both contractile dysfunction and structural damage to the myocardium.
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Transforming Growth Factor-β Function Blocking Prevents Myocardial Fibrosis and Diastolic Dysfunction in Pressure-Overloaded Rats
Fumitaka Kuwahara,Hisashi Kai,Keisuke Tokuda,Mamiko Kai,Akira Takeshita,Kensuke Egashira,Tsutomu Imaizumi +6 more
TL;DR: TGF-&bgr; plays a causal role in myocardial fibrosis and diastolic dysfunction through fibroblast activation in pressure-overloaded hearts and may provide an insight into a new therapeutic strategy to prevent myocardian fibrosis
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Reduction in serum cholesterol with pravastatin improves endothelium-dependent coronary vasomotion in patients with hypercholesterolemia.
Kensuke Egashira,Yoshitaka Hirooka,Hisashi Kai,Masaru Sugimachi,Satoshi O. Suzuki,Tetsuzi Inou,A. Takeshita +6 more
TL;DR: If cholesterol-lowering therapy improves endothelium-dependent coronary vasomotion in patients with hypercholesterolemia is investigated, acetylcholine-induced vasoconstriction of the epicardial coronary artery is found to be beneficial.