K
Keqing Wang
Researcher at Baylor College of Medicine
Publications - 28
Citations - 1368
Keqing Wang is an academic researcher from Baylor College of Medicine. The author has contributed to research in topics: Retinitis pigmentosa & Exome sequencing. The author has an hindex of 18, co-authored 25 publications receiving 1156 citations. Previous affiliations of Keqing Wang include Human Genome Sequencing Center.
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Journal ArticleDOI
Next generation sequencing-based molecular diagnosis of retinitis pigmentosa: identification of a novel genotype-phenotype correlation and clinical refinements
Feng Wang,Hui Wang,Han Fang Tuan,Duy H. Nguyen,Vincent Sun,Vafa Keser,Sara J. Bowne,Lori S. Sullivan,Hongrong Luo,Hongrong Luo,Ling Zhao,Ling Zhao,Xia Wang,Jacques Zaneveld,Jason S. Salvo,Sorath Noorani Siddiqui,Louise Mao,Dianna K. Wheaton,David G. Birch,Kari Branham,John R. Heckenlively,Cindy Wen,Ken Flagg,Henry Ferreyra,Jacqueline Pei,Ayesha Khan,Huanan Ren,Keqing Wang,Irma Lopez,Raheel Qamar,Raheel Qamar,Juan Carlos Zenteno,Raul Ayala-Ramirez,Beatriz Buentello-Volante,Qing Fu,David Simpson,Yumei Li,Ruifang Sui,Giuliana Silvestri,Stephen P. Daiger,Robert K. Koenekoop,Kang Zhang,Kang Zhang,Kang Zhang,Rui Chen +44 more
TL;DR: In this article, the authors performed a comprehensive molecular screening in a collection of 123 retinitis pigmentosa (RP) unsettled probands from a wide variety of ethnic backgrounds, including 113 unrelated simplex and 10 autosomal recessive RP (arRP) cases.
Journal ArticleDOI
Comprehensive molecular diagnosis of 179 Leber congenital amaurosis and juvenile retinitis pigmentosa patients by targeted next generation sequencing
Xia Wang,Hui Wang,Hui Wang,Vincent Sun,Han Fang Tuan,Vafa Keser,Keqing Wang,Huanan Ren,Irma Lopez,Jacques Zaneveld,Jacques Zaneveld,Sorath Noorani Siddiqui,Stephanie Bowles,Ayesha Khan,Jason S. Salvo,Jason S. Salvo,Samuel G. Jacobson,Alessandro Iannaccone,Feng Wang,Feng Wang,David G. Birch,John R. Heckenlively,Gerald A. Fishman,Elias I. Traboulsi,Yumei Li,Yumei Li,Dianna K H Wheaton,Robert K. Koenekoop,Rui Chen,Rui Chen +29 more
TL;DR: A novel gene and a large number of novel mutations that are associated with LCA/juvenile RP are identified and reclassified in two patients, highlighting the importance of molecular diagnosis as an integral part of clinical diagnosis.
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Genome-wide identification of direct targets of the Drosophila retinal determination protein Eyeless
Edwin J. Ostrin,Yumei Li,Kristi L. Hoffman,Jing Liu,Keqing Wang,Li Zhang,Graeme Mardon,Rui Chen +7 more
TL;DR: The results suggest that the integrated strategy of computational biology, genomics, and genetics is a powerful approach to identify direct downstream targets for any transcription factor genome-wide.
Journal ArticleDOI
Next‑generation sequencing‑based molecular diagnosis of 82 retinitis pigmentosa probands from Northern Ireland
Li Zhao,Feng Wang,Hui Wang,Yumei Li,Sharon Alexander,Keqing Wang,Colin E. Willoughby,Jacques Zaneveld,Lichun Jiang,Zachry T. Soens,Philip Earle,David Simpson,Giuliana Silvestri,Rui Chen +13 more
TL;DR: Next-generation sequencing-based, comprehensive molecular diagnoses are applied to a large number of RP probands from Northern Ireland, showing that molecular information can aid clinical diagnosis, potentially changing treatment options, current family counseling and management.
Journal ArticleDOI
Next-generation sequencing-based molecular diagnosis of a Chinese patient cohort with autosomal recessive retinitis pigmentosa.
Qing Fu,Feng Wang,Hui Wang,Fei Xu,Jacques Zaneveld,Huanan Ren,Vafa Keser,Irma Lopez,Han-Fang Tuan,Jason S. Salvo,Xia Wang,Li Zhao,Keqing Wang,Yumei Li,Robert K. Koenekoop,Rui Chen,Ruifang Sui +16 more
TL;DR: It is concluded that comprehensive molecular diagnosis can be vital for an accurate clinical diagnosis of RP and applying this tool on patients from different ethnic groups is essential for enhancing the knowledge of the global spectrum of RP disease-causing mutations.