K
Keri L.H. Carpenter
Researcher at University of Cambridge
Publications - 89
Citations - 5047
Keri L.H. Carpenter is an academic researcher from University of Cambridge. The author has contributed to research in topics: Traumatic brain injury & Microdialysis. The author has an hindex of 41, co-authored 82 publications receiving 4621 citations. Previous affiliations of Keri L.H. Carpenter include University of Barcelona.
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Journal ArticleDOI
Cerebral extracellular chemistry and outcome following traumatic brain injury: a microdialysis study of 223 patients
Ivan Timofeev,Keri L.H. Carpenter,Jurgens Nortje,Pippa G. Al-Rawi,M. T. O’Connell,Marek Czosnyka,Peter Smielewski,John D. Pickard,David K. Menon,Peter J. Kirkpatrick,Arun K. Gupta,Peter J. Hutchinson +11 more
TL;DR: The results of this study suggest that extracellular metabolic markers are independently associated with outcome following traumatic brain injury and whether treatment-related improvement in biochemistry translates into better outcome remains to be established.
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The cytokine response to human traumatic brain injury: temporal profiles and evidence for cerebral parenchymal production.
TL;DR: Evidence is provided for the cerebral production of these cytokines after severe TBI and they show a stereotyped temporal pattern after TBI.
Journal ArticleDOI
Consensus statement from the 2014 International Microdialysis Forum
Peter J. Hutchinson,Ibrahim Jalloh,Adel Helmy,Keri L.H. Carpenter,Elham Rostami,Bo Michael Bellander,Martyn G. Boutelle,Jeff W. Chen,Jan Claassen,Claire Dahyot-Fizelier,Per Enblad,Clare N. Gallagher,Raimund Helbok,Lars Hillered,Peter D. Le Roux,Sandra Magnoni,Halinder S. Mangat,David K. Menon,Carl-Henrik Nordström,Kristine O’Phelan,Mauro Oddo,Jon Pérez Bárcena,Claudia S. Robertson,Elisabeth Ronne-Engström,Juan Sahuquillo,Martin D. Smith,Nino Stocchetti,Antonio Belli,T. Adrian Carpenter,Jonathan P. Coles,Marek Czosnyka,Nil Dizdar,J. Clay Goodman,Arun K. Gupta,Troels H. Nielsen,Niklas Marklund,Ambroise Montcriol,M. T. O’Connell,Maria A. Poca,Asita Sarrafzadeh,Richard J. Shannon,Jane Skjøth-Rasmussen,Peter Smielewski,John F. Stover,Ivan Timofeev,Paul M. Vespa,Elizabeth Zavala,Urban Ungerstedt +47 more
TL;DR: A revised and updated consensus statement about the clinical use of microdialysis including technique, data interpretation, relationship with outcome, role in guiding therapy in neurocritical care and research applications is produced.
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The human brain utilizes lactate via the tricarboxylic acid cycle: a 13C-labelled microdialysis and high-resolution nuclear magnetic resonance study.
Clare N. Gallagher,Keri L.H. Carpenter,Peter Grice,Duncan J. Howe,Andrew Mason,Ivan Timofeev,David K. Menon,Peter J. Kirkpatrick,John D. Pickard,Garnette R. Sutherland,Peter J. Hutchinson +10 more
TL;DR: This is the first direct demonstration of brain utilization of lactate as an energy source in humans via the tricarboxylic acid cycle through cerebral microdialysis in patients with traumatic brain injury.
Journal ArticleDOI
Lipids and oxidised lipids in human atherosclerotic lesions at different stages of development
Keri L.H. Carpenter,S. E. Taylor,Carina van der Veen,Bridget K. Williamson,James A. Ballantine,Malcolm J. Mitchinson +5 more
TL;DR: Fatty streaks showed the highest concentration of 7 beta-hydroxycholesterol relative to cholesterol, and the lowest ratio of linoleate to oleate, suggesting that this type of lesion experiences the greatest concentration of free radical activity.