Kerstin Schreiber

TL;DR: The intuitive graphical user interface of MetaboliteDetector additionally allows for a detailed examination of a single GC/MS chromatogram including single ion chromatograms, recorded mass spectra, and identified metabolite spectra in combination with the corresponding reference spectra obtained from a reference library.

TL;DR: Genome-wide searches for additional components of the anaerobic metabolism identified potential genes for pyruvate-metabolizing NADH-dependent lactate dehydrogenase (ldhA), phosphotransacetylase (pta), and acetate kinase (ackA), which demonstrated the anr- and ihfA-dependent anaerilic induction of the ackA-pta promoter.

TL;DR: A cascade regulatory model for the fine-tuned genetic response of P. aeruginosa to anaerobic growth conditions in the presence of nitrate was deduced and NarXL in cooperation with Dnr is required for an aerobic nitrite reductase regulatory gene nirQ transcription.

TL;DR: This work describes the first description of an Anr-dependent, anaerobically induced, and functional Usp-like protein in bacteria, which might be essential for survival in deeper layers of a biofilm and the persistent infection of anaerobic mucus plaques in the cystic fibrosis lung.

TL;DR: The genome information and phenotypic data obtained in vitro and in a chicken infection model provided little evidence of fixed adaptation to a specific host, but the dominant C. jejuni ST-21 appeared to be characterized by phenotypesic flexibility and high genetic microdiversity, revealing properties of a generalist.