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Kevin A. Murach
Researcher at University of Kentucky
Publications - 66
Citations - 1564
Kevin A. Murach is an academic researcher from University of Kentucky. The author has contributed to research in topics: Skeletal muscle & Medicine. The author has an hindex of 18, co-authored 46 publications receiving 909 citations. Previous affiliations of Kevin A. Murach include University of Arkansas & College of Health Sciences, Bahrain.
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Journal ArticleDOI
MyoVision: software for automated high-content analysis of skeletal muscle immunohistochemistry.
Yuan Wen,Kevin A. Murach,Ivan J. Vechetti,Christopher S. Fry,Chase Daniel Vickery,Charlotte A. Peterson,John J. McCarthy,Kenneth S. Campbell +7 more
TL;DR: MyoVision is new software that overcomes limitations by performing high-content analysis of muscle cross sections with minimal manual input and improves upon previously reported automatic techniques and analyzes images without requiring significant human input and correction.
Journal ArticleDOI
Differential requirement for satellite cells during overload-induced muscle hypertrophy in growing versus mature mice
Kevin A. Murach,Kevin A. Murach,S.H. White,S.H. White,S.H. White,Yuan Wen,Angel Ho,Angel Ho,Esther E. Dupont-Versteegden,Esther E. Dupont-Versteegden,John J. McCarthy,Charlotte A. Peterson,Charlotte A. Peterson +12 more
TL;DR: Reliance on satellite cells for overload-induced hypertrophy is dependent on maturational age, and global responses to overload differ in young versus mature mice.
Journal ArticleDOI
Starring or supporting role? Satellite cells and skeletal muscle fiber size regulation
Kevin A. Murach,Christopher S. Fry,Tyler J. Kirby,Janna R. Jackson,Jonah D. Lee,S.H. White,Esther E. Dupont-Versteegden,John J. McCarthy,Charlotte A. Peterson +8 more
TL;DR: New evidence indicates that satellite cells play an important role in remodeling the extracellular matrix during hypertrophy and that hypertrophic adaptation proceeds in the absence of satellite cells in fully grown adult mice, but not in young growing mice.
Journal ArticleDOI
Skeletal Muscle Hypertrophy with Concurrent Exercise Training: Contrary Evidence for an Interference Effect
Kevin A. Murach,James R. Bagley +1 more
TL;DR: The purpose of this article is to outline the contrary evidence for an acute and chronic interference effect of concurrent exercise on skeletal muscle growth in humans and provide practical literature-based recommendations for maximizing hypertrophy when training concurrently.
Journal ArticleDOI
Myonuclear Domain Flexibility Challenges Rigid Assumptions on Satellite Cell Contribution to Skeletal Muscle Fiber Hypertrophy
Kevin A. Murach,Davis A. Englund,Esther E. Dupont-Versteegden,John J. McCarthy,John J. McCarthy,Charlotte A. Peterson +5 more
TL;DR: It is postulate that robust satellite cell activation and proliferation in response to mechanical loading is largely for these purposes, and the mechanisms by which Type 2 fibers can hypertrophy without additional myonuclei are elucidated.