K
Kenneth S. Campbell
Researcher at University of Kentucky
Publications - 147
Citations - 4324
Kenneth S. Campbell is an academic researcher from University of Kentucky. The author has contributed to research in topics: Myosin & Medicine. The author has an hindex of 32, co-authored 112 publications receiving 3538 citations. Previous affiliations of Kenneth S. Campbell include University of Birmingham & University of Wisconsin-Madison.
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Journal ArticleDOI
Effective fiber hypertrophy in satellite cell-depleted skeletal muscle.
John J. McCarthy,Jyothi Mula,Mitsunori Miyazaki,Rod A. Erfani,Kelcye Garrison,Amreen B. Farooqui,Ratchakrit Srikuea,Benjamin A. Lawson,Barry Grimes,Charles Keller,Gary Van Zant,Kenneth S. Campbell,Karyn A. Esser,Esther E. Dupont-Versteegden,Charlotte A. Peterson +14 more
TL;DR: Results provide convincing evidence that skeletal muscle fibers are capable of mounting a robust hypertrophic response to mechanical overload that is not dependent on satellite cells.
Journal ArticleDOI
Identification of the circadian transcriptome in adult mouse skeletal muscle.
John J. McCarthy,Jessica L. Andrews,Erin L. McDearmon,Kenneth S. Campbell,Brigham K. Barber,Brooke H. Miller,John R. Walker,John B. Hogenesch,Joseph S. Takahashi,Joseph S. Takahashi,Karyn A. Esser,Karyn A. Esser +11 more
TL;DR: Defining the circadian transcriptome in adult skeletal muscle and identifying the significant alterations in gene expression that occur in muscle of the Clock mutant mouse provide the basis for understanding the role of circadian rhythms in the daily maintenance of skeletal muscle.
Journal ArticleDOI
CLOCK and BMAL1 regulate MyoD and are necessary for maintenance of skeletal muscle phenotype and function
Jessica L. Andrews,Xiping Zhang,John J. McCarthy,Erin L. McDearmon,Troy A. Hornberger,Brenda Russell,Kenneth S. Campbell,Sandrine Arbogast,Michael B. Reid,John R. Walker,John B. Hogenesch,Joseph S. Takahashi,Karyn A. Esser,Karyn A. Esser +13 more
TL;DR: The identification of MyoD as a clock-controlled gene provides a mechanism by which the circadian clock may generate a muscle-specific circadian transcriptome in an adaptive role for the daily maintenance of adult skeletal muscle.
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Distinct growth hormone receptor signaling modes regulate skeletal muscle development and insulin sensitivity in mice
Mahendra D. Mavalli,Douglas J. DiGirolamo,Yong Fan,Ryan C. Riddle,Kenneth S. Campbell,Thomas van Groen,Stuart J. Frank,Stuart J. Frank,Mark A. Sperling,Karyn A. Esser,Marcas M. Bamman,Thomas L. Clemens +11 more
TL;DR: Different signaling pathways through which GHR regulates skeletal muscle development and modulates nutrient metabolism are identified, including marked peripheral adiposity, insulin resistance, and glucose intolerance.
Journal ArticleDOI
A cross-bridge mechanism can explain the thixotropic short-range elastic component of relaxed frog skeletal muscle
Kenneth S. Campbell,Martin Lakie +1 more
TL;DR: A theoretical model was developed in which the SREC and FRT arise as manifestations of a small number of slowly cycling cross‐bridges linking the actin and myosin filaments of a relaxed skeletal muscle and suggests that the cross‐bridge attachment rate must increase during interfilamentary movement.