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Kevin Arbuckle

Researcher at Swansea University

Publications -  50
Citations -  1660

Kevin Arbuckle is an academic researcher from Swansea University. The author has contributed to research in topics: Venom & Antivenom. The author has an hindex of 18, co-authored 46 publications receiving 1159 citations. Previous affiliations of Kevin Arbuckle include University of Liverpool.

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Widespread convergence in toxin resistance by predictable molecular evolution

TL;DR: Evidence of constrained convergent molecular evolution across the metazoan tree of life is provided by showing that resistance to toxic cardiac glycosides produced by plants and bufonid toads is mediated by similar molecular changes to the sodium-potassium-pump in insects, amphibians, reptiles, and mammals.
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A simple measure of the strength of convergent evolution

TL;DR: The Wheatsheaf index is developed that provides an index of the strength of convergent evolution incorporating both phenotypic similarity and phylogenetic relatedness and is comparable across any quantitative or semiquantitative traits and thus will enable the testing of various hypotheses relating to convergence.
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Differential procoagulant effects of saw-scaled viper (Serpentes: Viperidae: Echis) snake venoms on human plasma and the narrow taxonomic ranges of antivenom efficacies.

TL;DR: The results indicate that the venoms are, in general, potently procoagulant but that the relative dependence on calcium or phospholipid cofactors is highly variable and this will spur efforts into the development of antivenoms with more comprehensive coverage for bites not only from wild snakes but also from specimens widely kept in zoological collections.