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Kevin P. Cain
Researcher at Centers for Disease Control and Prevention
Publications - 84
Citations - 3147
Kevin P. Cain is an academic researcher from Centers for Disease Control and Prevention. The author has contributed to research in topics: Tuberculosis & Population. The author has an hindex of 23, co-authored 77 publications receiving 2799 citations. Previous affiliations of Kevin P. Cain include Urbana University & Liverpool John Moores University.
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Journal ArticleDOI
Xpert MTB/RIF Ultra for detection of Mycobacterium tuberculosis and rifampicin resistance: a prospective multicentre diagnostic accuracy study
Susan E. Dorman,Samuel G Schumacher,David Alland,Pamela Nabeta,Derek T. Armstrong,Bonnie S King,Sandra L. Hall,Soumitesh Chakravorty,Daniela Maria Cirillo,Nestani Tukvadze,Nino Bablishvili,Wendy S. Stevens,Lesley Scott,Camilla Rodrigues,Mubin Kazi,Moses Joloba,Lydia Nakiyingi,Mark P. Nicol,Mark P. Nicol,Yonas Ghebrekristos,Yonas Ghebrekristos,Irene Anyango,Wilfred Murithi,Reynaldo Dietze,Renata Lyrio Peres,Alena Skrahina,Vera Auchynka,Kamal Kishore Chopra,Mahmud Hanif,Xin Liu,Xing Yuan,Catharina Boehme,Jerrold J. Ellner,Claudia M. Denkinger,Yukari C. Manabe,David L. Hom,Rusudan Aspindzelashvili,Anura David,Utkarsha Surve,Louis Henry Kamulegeya,Sheila Nabweyambo,Shireen Surtie,Nchimunya Hapeela,Kevin P. Cain,Janet Agaya,Kimberly D. McCarthy,Patricia Marques-Rodrigues,Luiz Guilherme Schmidt Castellani,Pedro Sousa Almeida,Paola Poloni Lobo de Aguiar,Varvara Solodovnikova,Xianglin Ruan,Lili Liang,Guolong Zhang,Hong Zhu,Yingda Xie +55 more
TL;DR: For tuberculosis case detection, sensitivity ofXpert Ultra was superior to that of Xpert in Patients with paucibacillary disease and in patients with HIV, however, this increase in sensitivity came at the expense of a decrease in specificity.
Journal ArticleDOI
Development of a standardized screening rule for tuberculosis in people living with HIV in resource-constrained settings: individual participant data meta-analysis of observational studies.
Haileyesus Getahun,Wanitchaya Kittikraisak,Charles M. Heilig,Elizabeth L. Corbett,Helen Ayles,Helen Ayles,Kevin P. Cain,Alison D. Grant,Gavin J. Churchyard,Michael E. Kimerling,Sarita Shah,Stephen D. Lawn,Stephen D. Lawn,Robin Wood,Gary Maartens,Reuben Granich,Anand Date,Jay K. Varma +17 more
TL;DR: A simple, standardized tuberculosis screening rule for resource-constrained settings is reported, to identify people living with HIV who need further investigation for TB disease.
Journal ArticleDOI
Tuberculosis among foreign-born persons in the United States.
TL;DR: The relative yield of finding and treating latent TB infection is particularly high among individuals from most countries of sub-Saharan Africa and Southeast Asia.
Journal ArticleDOI
An Algorithm for Tuberculosis Screening and Diagnosis in People with HIV
Kevin P. Cain,Kimberly D. McCarthy,Charles M. Heilig,Patama Monkongdee,Theerawit Tasaneeyapan,Nong Kanara,Michael E. Kimerling,Phalkun Chheng,Sopheak Thai,Borann Sar,Praphan Phanuphak,Nipat Teeratakulpisarn,Nittaya Phanuphak,Nguyen Huy Dung,Hoang Thi Quy,Le Hung Thai,Jay K. Varma +16 more
TL;DR: It is likely that antiretroviral therapy and isoniazid preventive therapy can be started safely in people whose screening for all three symptoms is negative, whereas diagnosis in most others will require mycobacterial culture.
Journal ArticleDOI
Yield of Acid-fast Smear and Mycobacterial Culture for Tuberculosis Diagnosis in People with Human Immunodeficiency Virus
Patama Monkongdee,Kimberly D. McCarthy,Kevin P. Cain,Theerawit Tasaneeyapan,Nguyen Huy Dung,Nguyen Thi Ngoc Lan,Nguyen T. B. Yen,Nipat Teeratakulpisarn,Nibondh Udomsantisuk,Charles M. Heilig,Jay K. Varma +10 more
TL;DR: In people with HIV living in settings where mycobacterial culture is not routinely available to all patients, a third sputum smear adds little to the diagnosis of TB, and broth-based culture of three spUTum specimens diagnoses most TB cases.