H
Hong Zhu
Publications - 4
Citations - 546
Hong Zhu is an academic researcher. The author has contributed to research in topics: Tuberculosis & Mycobacterium tuberculosis. The author has an hindex of 3, co-authored 4 publications receiving 427 citations.
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Journal ArticleDOI
Xpert MTB/RIF Ultra for detection of Mycobacterium tuberculosis and rifampicin resistance: a prospective multicentre diagnostic accuracy study
Susan E. Dorman,Samuel G Schumacher,David Alland,Pamela Nabeta,Derek T. Armstrong,Bonnie S King,Sandra L. Hall,Soumitesh Chakravorty,Daniela Maria Cirillo,Nestani Tukvadze,Nino Bablishvili,Wendy S. Stevens,Lesley Scott,Camilla Rodrigues,Mubin Kazi,Moses Joloba,Lydia Nakiyingi,Mark P. Nicol,Mark P. Nicol,Yonas Ghebrekristos,Yonas Ghebrekristos,Irene Anyango,Wilfred Murithi,Reynaldo Dietze,Renata Lyrio Peres,Alena Skrahina,Vera Auchynka,Kamal Kishore Chopra,Mahmud Hanif,Xin Liu,Xing Yuan,Catharina Boehme,Jerrold J. Ellner,Claudia M. Denkinger,Yukari C. Manabe,David L. Hom,Rusudan Aspindzelashvili,Anura David,Utkarsha Surve,Louis Henry Kamulegeya,Sheila Nabweyambo,Shireen Surtie,Nchimunya Hapeela,Kevin P. Cain,Janet Agaya,Kimberly D. McCarthy,Patricia Marques-Rodrigues,Luiz Guilherme Schmidt Castellani,Pedro Sousa Almeida,Paola Poloni Lobo de Aguiar,Varvara Solodovnikova,Xianglin Ruan,Lili Liang,Guolong Zhang,Hong Zhu,Yingda Xie +55 more
TL;DR: For tuberculosis case detection, sensitivity ofXpert Ultra was superior to that of Xpert in Patients with paucibacillary disease and in patients with HIV, however, this increase in sensitivity came at the expense of a decrease in specificity.
Journal ArticleDOI
Evaluation of a Rapid Molecular Drug-Susceptibility Test for Tuberculosis
Yingda L. Xie,Soumitesh Chakravorty,Derek T. Armstrong,Sandra L. Hall,Laura E. Via,Taeksun Song,Xing Yuan,Xiaoying Mo,Hong Zhu,Peng Xu,Qian Gao,Myungsun Lee,Jong-Seok Lee,Laura E. Smith,Ray Y. Chen,Joon Sung Joh,Young Soo Cho,Xin Liu,Xianglin Ruan,Lili Liang,Nila J. Dharan,Sang Nae Cho,Clifton E. Barry,Clifton E. Barry,Jerrold J. Ellner,Susan E. Dorman,Susan E. Dorman,David Alland +27 more
TL;DR: This investigational assay accurately detected M. tuberculosis mutations associated with resistance to isoniazid, fluoroquinolones, and aminoglycosides and holds promise as a rapid point‐of‐care test to guide therapeutic decisions for patients with tuberculosis.
Journal ArticleDOI
Using biomarkers to predict TB treatment duration (Predict TB): a prospective, randomized, noninferiority, treatment shortening clinical trial
Ray Y. Chen,Laura E. Via,Laura E. Via,Lori E. Dodd,Gerhard Walzl,Stephanus T. Malherbe,Andre G. Loxton,Rodney Dawson,Robert J. Wilkinson,Robert J. Wilkinson,Robert J. Wilkinson,Friedrich Thienemann,Friedrich Thienemann,Michele Tameris,Mark Hatherill,Andreas H. Diacon,Xin Liu,Jin Xing,Xiaowei Jin,Zhenya Ma,Shouguo Pan,Guolong Zhang,Qian Gao,Qi Jiang,Hong Zhu,Lili Liang,Hongfei Duan,Taeksun Song,David Alland,Michael Tartakovsky,Alex Rosenthal,Christopher Whalen,Michael Duvenhage,Ying Cai,Lisa C. Goldfeder,Kriti Arora,Bronwyn Smith,Jill Winter,Clifton E. Barry,Clifton E. Barry +39 more
TL;DR: It is hypothesized that PET/CT characteristics at baseline,PET/CT changes at one month, and markers of residual bacterial load will identify patients with tuberculosis who can be cured with 4 months (16 weeks) of standard treatment.
Journal ArticleDOI
Radiological and functional evidence of the bronchial spread of tuberculosis: an observational analysis
Ray Y. Chen,Ray Y. Chen,Xiang Yu,Bronwyn Smith,Xin Liu,Jingcai Gao,Andreas H. Diacon,Rodney Dawson,Michele Tameris,Hong Zhu,Yahong Qu,Ruanqing Zhang,Shouguo Pan,Xiaowei Jin,Lisa C. Goldfeder,Ying Cai,Kriti Arora,Jing Wang,Joel Vincent,Stephanus T. Malherbe,Friedrich Thienemann,Friedrich Thienemann,Robert J. Wilkinson,Robert J. Wilkinson,Robert J. Wilkinson,Gerhard Walzl,Clifton E. Barry,Clifton E. Barry +27 more
TL;DR: In participants with pulmonary tuberculosis who were subsequently cured, the location of cavitary and non-cavitary lesions at baseline and new lesions at week 4 of treatment suggest a cavitary origin of disease and bronchial spread through the lungs.