K
Kiyoko Kato
Researcher at Kyushu University
Publications - 265
Citations - 5207
Kiyoko Kato is an academic researcher from Kyushu University. The author has contributed to research in topics: Medicine & Cancer. The author has an hindex of 33, co-authored 234 publications receiving 4435 citations. Previous affiliations of Kiyoko Kato include Juntendo University & University of North Carolina at Chapel Hill.
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Journal ArticleDOI
Isoprenoid addition to Ras protein is the critical modification for its membrane association and transforming activity
Kiyoko Kato,Adrienne D. Cox,Adrienne D. Cox,Mark M. Hisaka,Mark M. Hisaka,Suzanne M. Graham,Suzanne M. Graham,Janice E. Buss,Channing J. Der,Channing J. Der +9 more
TL;DR: One farnesylated mutant did not undergo either proteolysis or carboxyl methylation but still displayed efficient membrane association and transforming activity, indicating thatfarnesylation alone can support Ras transforming activity.
Journal ArticleDOI
A phase I and pharmacokinetic study of NK105, a paclitaxel-incorporating micellar nanoparticle formulation
Tetsuya Hamaguchi,Kiyoko Kato,Hisateru Yasui,C Morizane,Masataka Ikeda,Hikaru Ueno,Kei Muro,Yasuhide Yamada,Takuji Okusaka,Kuniaki Shirao,Yoshihisa Shimada,H. Nakahama,Yasuhiro Matsumura +12 more
TL;DR: The maximum tolerated dose (MTD), the dose-limiting toxicities (DLTs), the recommended dose (RD) for phase II, and the pharmacokinetics of NK105, a new polymeric micelle carrier system for paclitaxel (PTX) were examined.
Journal ArticleDOI
Characterization of side-population cells in human normal endometrium
Kiyoko Kato,Momoko Yoshimoto,Keiji Kato,Sawako Adachi,Asako Yamayoshi,Takahiro Arima,Kazuo Asanoma,Satoru Kyo,Tatsutoshi Nakahata,Norio Wake +9 more
TL;DR: SP cells in the human endometrium can function as progenitor cells and show long-term repopulating properties and produced gland- or stroma-like cells.
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FGFR2 gene amplification and clinicopathological features in gastric cancer
Kazuko Matsumoto,Tokuzo Arao,Tetsuya Hamaguchi,Yasuhiro Shimada,Kiyoko Kato,Ichiro Oda,Hirokazu Taniguchi,Fumiaki Koizumi,Kazuyoshi Yanagihara,Hiroki Sasaki,Kazuto Nishio,Yuki Yamada +11 more
TL;DR: The established PCR-based copy number assay could be a powerful tool for detecting FGFR2 amplification using FFPE samples and the results strongly encourage the development of FGFR-targeted therapy for gastric cancers with FGFR 2 amplification.
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ZAC, LIT1 (KCNQ1OT1) and p57KIP2 (CDKN1C) are in an imprinted gene network that may play a role in Beckwith–Wiedemann syndrome
Takahiro Arima,Tetsuya Kamikihara,Toshirou Hayashida,Kiyoko Kato,Toshiaki Inoue,Yasuaki Shirayoshi,Mitsuo Oshimura,Hidenobu Soejima,Tunehiro Mukai,Norio Wake +9 more
TL;DR: The data suggest that ZAC may regulate p57KIP2 through LIT1, forming part of a novel signaling pathway regulating cell growth, and contribute to Beckwith–Wiedemann syndrome.