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Klaus-Dieter Schlüter

Researcher at University of Giessen

Publications -  181
Citations -  5329

Klaus-Dieter Schlüter is an academic researcher from University of Giessen. The author has contributed to research in topics: Myocyte & Stimulation. The author has an hindex of 40, co-authored 170 publications receiving 4783 citations.

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Alterations of β-adrenergic signaling and cardiac hypertrophy in transgenic mice overexpressing TGF-β1

TL;DR: Transforming growth factor-β1 promotes or inhibits cell proliferation and induces fibrotic processes and extracellular matrix production in numerous cell types.
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Expression and function of soluble guanylate cyclase in pulmonary arterial hypertension

TL;DR: Stimulation of soluble guanylate cyclase with BAY 63-2521 partially reversed the PAH, the right heart hypertrophy and the structural remodelling of the lung vasculature, and may offer a new target for therapeutic intervention in pulmonary arterial hypertension.
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Cardiovascular actions of parathyroid hormone and parathyroid hormone-related peptide

TL;DR: It is suggested that increased plasma levels of PTH and PTH-rP influence cardiomyocyte and smooth muscle cell physiology and it can be assumed that PTH -rP acts as a paracrine or autocrine modulator in heart and vessels.
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Redox-sensitive intermediates mediate angiotensin II-induced p38 MAP kinase activation, AP-1 binding activity, and TGF-beta expression in adult ventricular cardiomyocytes.

TL;DR: This study identifies a previously unrecognized coupling of cardiac AT receptors to a NAD(P)H oxidase complex similar to that expressed in smooth muscle cells and identifies p38‐MAP kinase activation as an important downstream target.