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Saveria Femminò
Researcher at University of Turin
Publications - 39
Citations - 948
Saveria Femminò is an academic researcher from University of Turin. The author has contributed to research in topics: Cardioprotection & Reperfusion injury. The author has an hindex of 11, co-authored 33 publications receiving 594 citations.
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Journal ArticleDOI
Practical guidelines for rigor and reproducibility in preclinical and clinical studies on cardioprotection.
Hans Erik Bøtker,Derek J. Hausenloy,Ioanna Andreadou,Salvatore Antonucci,Kerstin Boengler,Sean M. Davidson,Soni Deshwal,Yvan Devaux,Fabio Di Lisa,Moises Di Sante,Panagiotis Efentakis,Saveria Femminò,David Garcia-Dorado,Zoltán Giricz,Borja Ibanez,Efstathios K. Iliodromitis,Nina Kaludercic,Petra Kleinbongard,Markus Neuhäuser,Michel Ovize,Pasquale Pagliaro,Michael Rahbek-Schmidt,Marisol Ruiz-Meana,Klaus-Dieter Schlüter,Rainer Schulz,Andreas Skyschally,Catherine D. E. Wilder,Derek M. Yellon,Péter Ferdinandy,Gerd Heusch +29 more
TL;DR: Hans Erik Bøtker’s aim is to contribute towards the humanizing of cycling in Europe by inspiring and inspiring the next generation of cyclists and runners.
Journal ArticleDOI
Pharmacological Inhibition of NLRP3 Inflammasome Attenuates Myocardial Ischemia/Reperfusion Injury by Activation of RISK and Mitochondrial Pathways.
Raffaella Mastrocola,Claudia Penna,Francesca Tullio,Saveria Femminò,Debora Nigro,Fausto Chiazza,Loredana Serpe,Debora Collotta,Giuseppe Alloatti,Mattia Cocco,Massimo Bertinaria,Pasquale Pagliaro,Manuela Aragno,Massimo Collino +13 more
TL;DR: It is demonstrated for the first time that INF4E protected against the IR-induced myocardial injury and dysfunction, by a mechanism that involves inhibition of the NLRP3 inflammasome, resulting in the activation of the prosurvival RISK pathway and improvement in mitochondrial function.
Journal ArticleDOI
From Molecular Mechanisms to Clinical Management of Antineoplastic Drug-Induced Cardiovascular Toxicity: A Translational Overview
Carlo G. Tocchetti,Christian Cadeddu,Daniela Di Lisi,Saveria Femminò,Rosalinda Madonna,Rosalinda Madonna,Donato Mele,Ines Monte,Giuseppina Novo,Claudia Penna,Alessia Pepe,Paolo Spallarossa,Gilda Varricchi,Gilda Varricchi,Concetta Zito,Pasquale Pagliaro,Giuseppe Mercuro +16 more
TL;DR: Patients undergoing anti-cancer treatments should be closely monitored, and patients at risk of CTX should be identified before beginning treatment to reduce CTX-related morbidity, according to the involvement of redox mechanisms in cancer biology and anticancer treatments.
Journal ArticleDOI
Extracellular vesicles and cardiovascular system: Biomarkers and Cardioprotective effectors
Saveria Femminò,Claudia Penna,Sara Margarita,Stefano Comità,Maria Felice Brizzi,Pasquale Pagliaro +5 more
TL;DR: This review focuses on the protective effects exerted by EVs, released by different cell types in the cardiovascular system, and the impact of EVs in cardioprotection after ischemia/reperfusion injury.
Journal ArticleDOI
Extracellular Vesicles From Adipose Stem Cells Prevent Muscle Damage and Inflammation in a Mouse Model of Hind Limb Ischemia: Role of Neuregulin-1.
Federico Figliolini,Andrea Ranghino,Cristina Grange,Massimo Cedrino,Marta Tapparo,Claudia Cavallari,Andrea Rossi,Gabriele Togliatto,Saveria Femminò,Maria Vittoria Gugliuzza,Giovanni Camussi,Maria Felice Brizzi +11 more
TL;DR: In this paper, critical hindlimb ischemia is a severe consequence of peripheral artery disease, and surgical treatment does not prevent skeletal muscle impairment or improve long-term patient outcomes.