K
Konstantin P. Volcho
Researcher at Russian Academy of Sciences
Publications - 270
Citations - 2816
Konstantin P. Volcho is an academic researcher from Russian Academy of Sciences. The author has contributed to research in topics: Catalysis & Chemistry. The author has an hindex of 24, co-authored 241 publications receiving 2288 citations. Previous affiliations of Konstantin P. Volcho include Novosibirsk State University.
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Journal ArticleDOI
Synthesis and biological evaluation of novel tyrosyl-DNA phosphodiesterase 1 inhibitors with a benzopentathiepine moiety.
Alexandra L. Zakharenko,T. M. Khomenko,T. M. Khomenko,Svetlana Zhukova,Olga A. Koval,Olga A. Koval,Olga D. Zakharova,Rashid O. Anarbaev,Rashid O. Anarbaev,Natalya Sh. Lebedeva,Natalya Sh. Lebedeva,Dina V. Korchagina,Nina I. Komarova,Vladimir Vasiliev,Jóhannes Reynisson,Konstantin P. Volcho,Konstantin P. Volcho,Nariman F. Salakhutdinov,Nariman F. Salakhutdinov,Olga I. Lavrik,Olga I. Lavrik +20 more
TL;DR: The study of cytotoxicity of these compounds revealed that all compounds cause an apoptotic cell death in MCF-7 and Hep G2 cells, therefore the new class of very effective inhibitors of TDP1 was elaborated.
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Monoterpenes as a renewable source of biologically active compounds
TL;DR: In this article, a review of various types of biological activity exhibited by monoterpenes and their derivatives, including analgesic, anti-inflammatory, anticonvulsant, antidepressant and anti-Alzheimer, antiParkinsonian, antiviral, and antibacterial (anti-tuberculosis) effects is presented.
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Functional supramolecular systems: design and applications
Igor S. Antipin,Igor S. Antipin,Mikhail V. Alfimov,Vladimir V. Arslanov,Vladimir Burilov,Sergey Z. Vatsadze,Yan Z. Voloshin,Konstantin P. Volcho,Valery V. Gorbatchuk,Yulia G. Gorbunova,Sergey P. Gromov,Sergey P. Gromov,Semyon V. Dudkin,Sergei Yu. Zaitsev,Lucia Ya. Zakharova,Marat A. Ziganshin,Anna Zolotukhina,Anna Zolotukhina,Maria A. Kalinina,Karakhanov Eduard A,Ruslan R. Kashapov,Oskar I. Koifman,Oskar I. Koifman,Alexander I. Konovalov,Vladimir S. Korenev,A. L. Maksimov,A. L. Maksimov,Nugzar Zh. Mamardashvili,Galina M. Mamardashvili,Alexander G. Martynov,Asiya R. Mustafina,R. I. Nugmanov,A. S. Ovsyannikov,Pavel L. Padnya,Andrei S. Potapov,Sofiya L. Selektor,Maxim N. Sokolov,Svetlana E. Solovieva,Svetlana E. Solovieva,Ivan I. Stoikov,Pavel A. Stuzhin,E. V. Suslov,Evgeny N. Ushakov,Vladimir P. Fedin,Svetlana V. Fedorenko,Olga A. Fedorova,Yury V. Fedorov,Sergei N. Chvalun,Sergei N. Chvalun,Aslan Yu. Tsivadze,Sergei N. Shtykov,D. N. Shurpik,Maxim A. Shcherbina,Maxim A. Shcherbina,Luidmila S. Yakimova +54 more
TL;DR: The interest in functional supramolecular systems for the design of innovative materials and technologies, able to fundamentally change the world, is growing at a high pace as discussed by the authors, and the huge array of publications in recent years in the global literature calls for systematization of the structural trends inherent in the formation of these systems revealed at different molecular platforms and practically useful properties they exhibit.
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Reactions of Allyl Alcohols of the Pinane Series and of Their Epoxides in the Presence of Montmorillonite Clay
Irina V. Il'ina,Konstantin P. Volcho,Dina V. Korchagina,Vladimir A. Barkhash,Nariman F. Salakhutdinov +4 more
TL;DR: In this paper, the reactivity of allyl alcohols of the pinane series and of their epoxides in the presence of montmorillonite clay in intra-and intermolecular reactions was studied.
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Highly Potent Activity of (1R,2R,6S)-3-Methyl-6-(prop-1-en-2-yl)cyclohex-3-ene-1,2-diol in Animal Models of Parkinson’s Disease
O. V. Ardashov,Alla Pavlova,Irina V. Il'ina,Ekaterina A. Morozova,Dina V. Korchagina,Elena V. Karpova,Konstantin P. Volcho,Tatyana G. Tolstikova,Nariman F. Salakhutdinov +8 more
TL;DR: The use of compound 1 resulted in nearly full recovery of the locomotor and exploratory activities and was as effective as the comparator agent (levodopa) in both MPTP and haloperidol animal models.