K
Konstantinos Gerasimidis
Researcher at University of Glasgow
Publications - 158
Citations - 3555
Konstantinos Gerasimidis is an academic researcher from University of Glasgow. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 25, co-authored 124 publications receiving 2282 citations. Previous affiliations of Konstantinos Gerasimidis include American Hotel & Lodging Educational Institute & Glasgow Royal Infirmary.
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Journal ArticleDOI
The Medical Management of Paediatric Crohn's Disease: an ECCO-ESPGHAN Guideline Update.
Patrick F. van Rheenen,Marina Aloi,Amit Assa,Jiri Bronsky,Johanna C. Escher,Ulrika L. Fagerberg,Marco Gasparetto,Konstantinos Gerasimidis,Anne M. Griffiths,Paul Henderson,Sibylle Koletzko,Sibylle Koletzko,Kaija-Leena Kolho,Arie Levine,Johan Van Limbergen,Francisco Javier Martin de Carpi,Víctor Manuel Navas-López,Salvatore Oliva,Lissy de Ridder,Richard K Russell,Dror S. Shouval,Dror S. Shouval,Antonino Spinelli,Dan Turner,David C. Wilson,Eytan Wine,Frank M. Ruemmele,Frank M. Ruemmele +27 more
TL;DR: An evidence-supported update of the ECCO-ESPGHAN guideline on the medical management of paediatric Crohn's disease is provided, establishing that it was key to identify patients at high risk of a complicated disease course at the earliest opportunity to reduce bowel damage.
Journal ArticleDOI
Extensive Modulation of the Fecal Metagenome in Children With Crohn's Disease During Exclusive Enteral Nutrition
Christopher Quince,Umer Zeeshan Ijaz,Nicholas J. Loman,A. Murat Eren,Delphine M. Saulnier,Julie Russell,Sarah J. Haig,Szymon T. Calus,Joshua Quick,Andrew H. Barclay,Martin Bertz,Michael Blaut,Richard Hansen,Paraic McGrogan,Richard K. Russell,Christine A. Edwards,Konstantinos Gerasimidis +16 more
TL;DR: Disease improvement following treatment with EEN is associated with extensive modulation of the gut microbiome, and the microbiota of CD patients had a broader functional capacity than healthy controls, but diversity decreased with E EN.
Journal ArticleDOI
Treatment of active Crohn's disease with an ordinary food-based diet that replicates exclusive enteral nutrition.
Vaios Svolos,Richard Hansen,Ben Nichols,Christopher Quince,Umer Zeeshan Ijaz,Rodanthi Papadopoulou,Christine A. Edwards,David G. Watson,Adel Alghamdi,Asker Daniel Brejnrod,C Ansalone,Hazel Duncan,Lisa Gervais,Rachel Tayler,Jonathan Salmond,Daniele Bolognini,Robert Klopfleisch,Daniel R. Gaya,Simon Milling,Richard K. Russell,Konstantinos Gerasimidis +20 more
TL;DR: CD-TREAT replicates EEN changes in the microbiome, decreases gut inflammation, is well tolerated, and is potentially effective in patients with active CD.
Journal ArticleDOI
Role of Gut Microbiota in the Aetiology of Obesity: Proposed Mechanisms and Review of the Literature.
Muhammad Jaffar Khan,Muhammad Jaffar Khan,Konstantinos Gerasimidis,Christine A. Edwards,M Guftar Shaikh +4 more
TL;DR: Evidence from animal and human studies clearly indicates controversies in determining the cause or effect relationship between the gut microbiota and obesity, and metagenomics based studies indicate that functionality rather than the composition of gut microbiota may be important.
Journal ArticleDOI
Decline in presumptively protective gut bacterial species and metabolites are paradoxically associated with disease improvement in pediatric Crohn's disease during enteral nutrition
Konstantinos Gerasimidis,Konstantinos Gerasimidis,Martin Bertz,Laura Hanske,Jana Junick,Olga Biskou,Margarita Aguilera,Vikki Garrick,Richard K. Russell,Richard K. Russell,Michael Blaut,Paraic McGrogan,Paraic McGrogan,Christine A. Edwards +13 more
TL;DR: The results do challenge the current perception of a protective role for F. prausnitzii in CD, and EEN microbiota diversity increased when the children returned to their free diet.