R
Richard K. Russell
Researcher at University of Edinburgh
Publications - 119
Citations - 5701
Richard K. Russell is an academic researcher from University of Edinburgh. The author has contributed to research in topics: Inflammatory bowel disease & Ulcerative colitis. The author has an hindex of 30, co-authored 119 publications receiving 4507 citations. Previous affiliations of Richard K. Russell include Royal Devon and Exeter Hospital & University of Glasgow.
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Journal ArticleDOI
Definition of Phenotypic Characteristics of Childhood-Onset Inflammatory Bowel Disease
Johan Van Limbergen,Johan Van Limbergen,Johan Van Limbergen,Richard K. Russell,Hazel E. Drummond,Marian C Aldhous,Nicola K. Round,Nicola K. Round,Elaine R. Nimmo,Linda Smith,Peter M. Gillett,Paraic McGrogan,Lawrence T. Weaver,W. Michael Bisset,Gamal Mahdi,Ian D. Arnott,Jack Satsangi,David C. Wilson,David C. Wilson +18 more
TL;DR: Childhood-onset IBD is characterized by extensive intestinal involvement and rapid early progression, characterized by a "panenteric" phenotype.
Journal ArticleDOI
Management of Pediatric Ulcerative Colitis: Joint ECCO and ESPGHAN Evidence-based Consensus Guidelines
Dan Turner,Arie Levine,Johanna C. Escher,Anne M. Griffiths,Richard K. Russell,Axel Dignass,Jorge Amil Dias,Jiri Bronsky,Christian Braegger,Salvatore Cucchiara,Lissy de Ridder,Ulrika L. Fagerberg,Seamus Hussey,Jean-Pierre Hugot,Sanja Kolaček,Kaija-Leena Kolho,Paolo Lionetti,Anders Paerregaard,Alexander Potapov,Risto Rintala,Daniela Elena Serban,Annamaria Staiano,Brian Sweeny,Gigi Veerman,Gábor Veres,David C. Wilson,Frank M. Ruemmele +26 more
TL;DR: These guidelines provide clinically useful points to guide the management of UC in children and offer a standardized protocol that allows effective, timely management and monitoring of the disease course, while acknowledging that each patient is unique.
Journal ArticleDOI
Diverse genome-wide association studies associate the IL12/IL23 pathway with Crohn Disease.
Kai Wang,Haitao Zhang,Subra Kugathasan,Vito Annese,Jonathan P. Bradfield,Richard K. Russell,Patrick M. A. Sleiman,Marcin Imielinski,Joseph T. Glessner,Cuiping Hou,David C. Wilson,Thomas D. Walters,Cecilia Kim,Edward C. Frackelton,Paolo Lionetti,Arrigo Barabino,Johan Van Limbergen,Stephen L. Guthery,Lee A. Denson,David A. Piccoli,Mingyao Li,Marla Dubinsky,Mark S. Silverberg,Anne M. Griffiths,Struan F.A. Grant,Struan F.A. Grant,Jack Satsangi,Robert N. Baldassano,Hakon Hakonarson,Hakon Hakonarson +29 more
TL;DR: This study applied pathway analysis using Affymetrix SNP genotype data from theWTCCC and uncovered significant association between Crohn Disease and the IL12/IL23 pathway, harboring 20 genes.
Journal ArticleDOI
Management of Paediatric Ulcerative Colitis, Part 1: Ambulatory Care-An Evidence-based Guideline From European Crohn's and Colitis Organization and European Society of Paediatric Gastroenterology, Hepatology and Nutrition.
Dan Turner,Frank M. Ruemmele,Esther Orlanski-Meyer,Anne M. Griffiths,Javier Martín de Carpi,Jiri Bronsky,Gábor Veres,Marina Aloi,Caterina Strisciuglio,Christian Braegger,Amit Assa,Claudio Romano,Seamus Hussey,Michael Stanton,Mikko P. Pakarinen,Lissy de Ridder,Konstantinos H. Katsanos,Nicholas M. Croft,Víctor Manuel Navas-López,David C. Wilson,Sally Lawrence,Richard K. Russell +21 more
TL;DR: These guidelines provide a guide to clinicians managing children with UC and IBD-unclassified management to provide modern management strategies while maintaining vigilance around appropriate outcomes and safety issues.
Journal ArticleDOI
New genes in inflammatory bowel disease: lessons for complex diseases?
TL;DR: The recent advances in the genetics of inflammatory bowel disease are reviewed, with particular emphasis on the data that have been generated since the discovery of the CARD15 (NOD2) gene in 2001.