K
Koon Hou Mak
Researcher at Gleneagles Hospital
Publications - 18
Citations - 3242
Koon Hou Mak is an academic researcher from Gleneagles Hospital. The author has contributed to research in topics: Clopidogrel & Myocardial infarction. The author has an hindex of 14, co-authored 18 publications receiving 3108 citations. Previous affiliations of Koon Hou Mak include National University of Singapore & Cleveland Clinic.
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Journal ArticleDOI
Clopidogrel and Aspirin versus Aspirin Alone for the Prevention of Atherothrombotic Events
Deepak L. Bhatt,Keith A.A. Fox,Werner Hacke,Peter B. Berger,Henry R. Black,William E. Boden,Patrice Cacoub,Eric A. Cohen,Mark A. Creager,J. Donald Easton,Marcus Flather,Steven M. Haffner,Christian W. Hamm,Graeme J. Hankey,S. Claiborne Johnston,Koon Hou Mak,Jean-Louis Mas,Gilles Montalescot,Thomas A. Pearson,P. Gabriel Steg,Steven R. Steinhubl,Michael A. Weber,Danielle M. Brennan,Liz Fabry-Ribaudo,Joan E. Booth,Eric J. Topol +25 more
TL;DR: In this article, the authors compared the effect of clopidogrel and low-dose aspirin on the rate of myocardial infarction, stroke, or death from cardiovascular causes.
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Incomplete inhibition of thromboxane biosynthesis by acetylsalicylic acid: determinants and effect on cardiovascular risk.
John W. Eikelboom,Graeme J. Hankey,J. Thom,Deepak L. Bhatt,P. Gabriel Steg,Gilles Montalescot,S. Claiborne Johnston,Steven R. Steinhubl,Koon Hou Mak,J. Donald Easton,Christian W. Hamm,Tingfei Hu,Keith A.A. Fox,Eric J. Topol +13 more
TL;DR: In aspirin-treated patients, urinary concentrations of 11-dehydro thromboxane B2 are an externally valid and potentially modifiable determinant of stroke, myocardial infarction, or cardiovascular death in patients at risk for atherothrombotic events.
Journal ArticleDOI
Heparin-induced thrombocytopenia.
TL;DR: Heparin-induced thrombocytopenia (HIT) is a potentially serious complication of heparin therapy and is being encountered more frequently in patients with cardiovascular disease as use of anticoagulant therapy becomes more widespread.
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Effect of clopidogrel plus ASA vs. ASA early after TIA and ischaemic stroke: a substudy of the CHARISMA trial.
Graeme J. Hankey,S. Claiborne Johnston,J. Donald Easton,Werner Hacke,Jean-Louis Mas,Danielle M. Brennan,Koon Hou Mak,Deepak L. Bhatt,Keith A.A. Fox,Eric J. Topol +9 more
TL;DR: The data are consistent with, but do not prove the hypothesis that early addition of clopidogrel to acetylsalicylic acid in patients with transient ischaemic attack and ischaemia stroke of arterial origin may be more effective and acceptably safe compared with acetyl salicylic Acid alone.
Journal ArticleDOI
Platelet glycoprotein IIb/IIIa inhibition in acute coronary syndromes.
Koon Hou Mak,David J. Moliterno +1 more
TL;DR: To further improve outcomes in this high-risk group of patients, strategies pertaining to prolonged periods of vessel passivation with oral formulations and early or delayed invasive approaches are being studied.