K
Kouki Matsuda
Researcher at Kumamoto University
Publications - 47
Citations - 667
Kouki Matsuda is an academic researcher from Kumamoto University. The author has contributed to research in topics: Medicine & Antibody. The author has an hindex of 13, co-authored 38 publications receiving 435 citations.
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Journal ArticleDOI
GRL-0920, an Indole Chloropyridinyl Ester, Completely Blocks SARS-CoV-2 Infection.
Shin-ichiro Hattori,Nobuyo Higshi-Kuwata,Jakka Raghavaiah,Debananda Das,Haydar Bulut,David A. Davis,Yuki Takamatsu,Kouki Matsuda,Nobutoki Takamune,Naoki Kishimoto,Tadashi Okamura,Shogo Misumi,Robert Yarchoan,Kenji Maeda,Arun K. Ghosh,Hiroaki Mitsuya,Hiroaki Mitsuya +16 more
TL;DR: GRL-0920 might serve as a potential therapeutic for coronavirus disease 2019 (COVID-19) and might be optimized to generate more-potent anti-SARS-CoV-2 compounds to shed light on the development of therapeutics for CO VID-19.
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A novel highly quantitative and reproducible assay for the detection of anti-SARS-CoV-2 IgG and IgM antibodies.
Kenta Noda,Kouki Matsuda,Shigehiro Yagishita,Kenji Maeda,Yutaro Akiyama,Junko Terada-Hirashima,Hiromichi Matsushita,Satoshi Iwata,Kazuto Yamashita,Yusuke Atarashi,Shunsuke Watanabe,Nobuyuki Ide,Tomokazu Yoshida,Norio Ohmagari,Hiroaki Mitsuya,Hiroaki Mitsuya,Akinobu Hamada +16 more
TL;DR: In this article, the authors developed a diagnostic test that detects SARS-CoV-2 IgG and IgM with high quantitativeness and reproducibility and low interference.
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Inhibition of autophagy by chloroquine induces apoptosis in primary effusion lymphoma in vitro and in vivo through induction of endoplasmic reticulum stress
TL;DR: It is shown here for the first time that the inhibition of autophagy induces ER stress-mediated apoptosis in PEL cells, a novel strategy for cancer chemotherapy.
Journal ArticleDOI
Inhibition of HIV-1 replication by a tricyclic coumarin GUT-70 in acutely and chronically infected cells.
Eriko Kudo,Manabu Taura,Kouki Matsuda,Masako Shimamoto,Ryusho Kariya,Hiroki Goto,Shinichiro Hattori,Shinya Kimura,Seiji Okada +8 more
TL;DR: The results strengthen the idea that NF-κB pathway is one of the potential targets to control HIV-1 replication and that GUT-70 could serve as a lead compound to develop novel therapeutic agents against HIV- 1 infection.
Journal ArticleDOI
Combination of a Latency-Reversing Agent With a Smac Mimetic Minimizes Secondary HIV-1 Infection in vitro
Shin-ichiro Hattori,Kouki Matsuda,Kiyoto Tsuchiya,Hiroyuki Gatanaga,Shinichi Oka,Kazuhisa Yoshimura,Hiroaki Mitsuya,Kenji Maeda +7 more
TL;DR: The results suggest that the combination of an LRA and an “apoptosis-inducing” agent, such as a Smac mimetic, is a possible treatment option to decrease HIV-1 reservoirs without the occurrence of HIV- 1 production by reactivated cells.