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Krishna Kumar Gnanasekaran

Researcher at Oklahoma State University–Stillwater

Publications -  22
Citations -  114

Krishna Kumar Gnanasekaran is an academic researcher from Oklahoma State University–Stillwater. The author has contributed to research in topics: Nucleophile & Chloride. The author has an hindex of 6, co-authored 21 publications receiving 98 citations.

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Efficient synthesis of 1,3,4-oxadiazoles promoted by NH4Cl

TL;DR: In this article, an efficient and inexpensive approach to the synthesis of 2-substituted and 2,5-disubstitized 1,3,4oxadiazoles from arylhydrazides and orthoesters is reported using catalytic NH4Cl.
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Synthesis and evaluation of second generation Flex-Het scaffolds against the human ovarian cancer A2780 cell line.

TL;DR: A gradient of activities was observed as the substituent on the aryl ring was altered, and specific members with the 4-atom acrylamide linker did exhibit excellent potency, but the efficacy was slightly below that of SHetA2.
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Pyrazoloquinazolinones and pyrazolopyridopyrimidinones by a sequential N-acylation–SNAr reaction

TL;DR: In this paper, an efficient synthesis of pyrazolo[1,5- a ]quinazolin-5(4 H )-ones and pyrido[3,2- e ]pyrimidin-1.5amino-1 H -pyrazoles is reported from the reaction of 2-haloaroyl chlorides with 5-amino 1 H pyrazoles, taking advantage of the 1,3-disposition of electrophilic centers in the acid chloride and the similar arrangement of nucleophilic sites in the pyraz