K
Kristina Elfgren
Researcher at Karolinska University Hospital
Publications - 23
Citations - 3095
Kristina Elfgren is an academic researcher from Karolinska University Hospital. The author has contributed to research in topics: Cervical intraepithelial neoplasia & Cervical cancer. The author has an hindex of 14, co-authored 23 publications receiving 2970 citations. Previous affiliations of Kristina Elfgren include Karolinska Institutet.
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Journal ArticleDOI
High sustained efficacy of a prophylactic quadrivalent human papillomavirus types 6/11/16/18 L1 virus-like particle vaccine through 5 years of follow-up
Luisa L. Villa,Ronaldo L.R. Costa,Carlos Alberto Petta,Rosires Pereira de Andrade,Jorma Paavonen,O-E Iversen,S-E Olsson,J. Hoye,Margareta Steinwall,G. Riis-Johannessen,A. Andersson-Ellstrom,Kristina Elfgren,G. Von Krogh,Matti Lehtinen,Christian Malm,Gretchen M. Tamms,Katherine E.D. Giacoletti,Lisa Lupinacci,Radha Railkar,Frank J. Taddeo,Janine T. Bryan,Mark T. Esser,Heather L. Sings,Alfred Saah,Eliav Barr +24 more
TL;DR: A prophylactic quadrivalent HPV vaccine was effective through 5 years for prevention of persistent infection and disease caused by HPV 6/11/16/18, and this duration supports vaccination of adolescents and young adults.
Journal ArticleDOI
Human Papillomavirus and Papanicolaou Tests to Screen for Cervical Cancer
Pontus Naucler,Walter Ryd,Sven Törnberg,Anders Strand,Göran Wadell,Kristina Elfgren,Thomas Rådberg,Björn Strander,Bo Johansson,Ola Forslund,Bengt-Göran Hansson,Eva Rylander,Joakim Dillner +12 more
TL;DR: The addition of an HPV test to the Pap test to screen women in their mid-30s for cervical cancer reduces the incidence of grade 2 or 3 cervical intraepithelial neoplasia or cancer detected by subsequent screening examinations.
Journal ArticleDOI
Induction of immune memory following administration of a prophylactic quadrivalent human papillomavirus (HPV) types 6/11/16/18 L1 virus-like particle (VLP) vaccine
Sven-Eric Olsson,Luisa L. Villa,Ronaldo L.R. Costa,Carlos Alberto Petta,Rosires Pereira de Andrade,Christian Malm,Ole-Erik Iversen,John Høye,Margareta Steinwall,Grete Riis-Johannessen,Agneta Andersson-Ellstrom,Kristina Elfgren,Geo von Krogh,Matti Lehtinen,Jorma Paavonen,Gretchen M. Tamms,Katherine E.D. Giacoletti,Lisa Lupinacci,Mark T. Esser,Scott Vuocolo,Alfred Saah,Eliav Barr +21 more
TL;DR: A three-dose regimen of quadrivalent HPV vaccine induces high efficacy and stable anti-HPV levels for at least 5 years, suggesting that the efficacy of this vaccine will be long lasting.
Journal ArticleDOI
Efficacy of HPV DNA testing with cytology triage and/or repeat HPV DNA testing in primary cervical cancer screening.
Pontus Naucler,Walter Ryd,Sven Törnberg,Anders Strand,Göran Wadell,Kristina Elfgren,Thomas Rådberg,Björn Strander,Ola Forslund,Bengt-Göran Hansson,Björn Hagmar,Bo Johansson,Eva Rylander,Joakim Dillner +13 more
TL;DR: Primary HPV DNA-based screening with cytology triage and repeat HPV DNA testing of cytology-negative women appears to be the most feasible cervical screening strategy.
Journal ArticleDOI
Human Papillomavirus and Papanicolaou Tests to Screen for Cervical Cancer
Pontus Naucler,Walter Ryd,Sven Törnberg,Anders Strand,Göran Wadell,Kristina Elfgren,Thomas Rådberg,Björn Strander,Ola Forslund,Bengt-Göran Hansson,Eva Rylander,Joakim Dillner +11 more
TL;DR: The improved sensitivity of HPV testing in women in their mid-30s who are screened for cervical cancer is not solely a result of over-diagnosis, and can be ascribed-at least in part-to the earlier diagnosis of cervical lesions that do not regress on follow-up screening.