K
Kristina Holmberg
Researcher at Karolinska Institutet
Publications - 57
Citations - 2074
Kristina Holmberg is an academic researcher from Karolinska Institutet. The author has contributed to research in topics: Galanin & Neuropeptide. The author has an hindex of 26, co-authored 56 publications receiving 2016 citations. Previous affiliations of Kristina Holmberg include California Institute of Technology & Halmstad University.
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Cocaine- and amphetamine-regulated transcript in the rat vagus nerve: A putative mediator of cholecystokinin-induced satiety
TL;DR: The present results suggest that CART-derived peptides are present in vagal afferent neurons sensitive to cholecystokinin, suggesting that the role of these peptides in feeding may be explained partly by mediating postprandial satiety effects of chole cysteine.
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Expression and regulation of cholecystokinin and cholecystokinin receptors in rat nodose and dorsal root ganglia.
TL;DR: Results demonstrate that the CCK(A)-R is expressed by both viscero- and somatosensory primary sensory neurons, supporting a role for this receptor as a mediator both of CCK-induced satiety and in sensory processing at the spinal level.
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Suppressed kindling epileptogenesis in mice with ectopic overexpression of galanin
Merab Kokaia,Kristina Holmberg,Avtandil Nanobashvili,Zhi-Qing David Xu,Zaal Kokaia,Urban Lendahl,Susanne Hilke,Elvar Theodorsson,Ulrika Kahl,Tamas Bartfai,Olle Lindvall,Tomas Hökfelt +11 more
TL;DR: Evidence is provided that ectopically overexpressed galanin can be released and dampen the development of epilepsy by means of receptor-mediated action, at least partly by reducing glutamate release from mossy fibers.
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Expression and regulation of the neuropeptide Y Y2 receptor in sensory and autonomic ganglia
Xu Zhang,Tiejun Shi,Kristina Holmberg,Marc Landry,Wenjin Huang,Hua-Sheng Xiao,Gong Ju,Tomas Hökfelt +7 more
TL;DR: Y2R mRNA levels increase in rat spinal motoneurons after axotomy, and under normal circumstances NPY may act on Y1 and Y2Rs expressed, respectively, in small and large CGRP-positive DRG neurons in the rat.
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Effect of axotomy on expression of NPY, galanin, and NPY Y1 and Y2 receptors in dorsal root ganglia and the superior cervical ganglion studied with double-labeling in situ hybridization and immunohistochemistry.
TL;DR: The results demonstrate that double-labeling procedures are valid tools to quantitatively evaluate coexistence situations in sensory and sympathetic ganglia, showing a high degree of coexistence for NPY and galanin in axotomized neurons both in the lumbar 5 DRG and in the SCG.