Z
Zhi-Qing David Xu
Researcher at Capital Medical University
Publications - 76
Citations - 3392
Zhi-Qing David Xu is an academic researcher from Capital Medical University. The author has contributed to research in topics: Galanin & Neuropeptide. The author has an hindex of 30, co-authored 73 publications receiving 3089 citations. Previous affiliations of Zhi-Qing David Xu include Huazhong University of Science and Technology & Karolinska Institutet.
Papers
More filters
Journal ArticleDOI
Neuropeptides--an overview
Tomas Hökfelt,Christian Broberger,Zhi-Qing David Xu,Valeriy Sergeyev,Ruud Ubink,Margarita Diez +5 more
TL;DR: It seems that peptides may play a role particularly when the nervous system is stressed, challenged or afflicted by disease, and that peptidergic systems may, therefore, be targets for novel therapeutic strategies.
Journal ArticleDOI
Galanin/GMAP- and NPY-like immunoreactivities in locus coeruleus and noradrenergic nerve terminals in the hippocampal formation and cortex with notes on the galanin-R1 and -R2 receptors.
TL;DR: By using immunofluorescence methodology, extensive galanin (GAL) and GAL message‐associated peptide (GMAP)‐positive terminal networks were observed in the hippocampal formation, and the majority of the GAL/GMAP fibers were dopamine β‐hydroxylase‐ (DBH) positive, that is, they were noradrenergic.
Journal ArticleDOI
Anxiolytic- and antidepressant-like profiles of the galanin-3 receptor (Gal3) antagonists SNAP 37889 and SNAP 398299
Chad J. Swanson,Thomas P. Blackburn,Xuexiang Zhang,Kang Zheng,Zhi-Qing David Xu,Tomas Hökfelt,Toni D. Wolinsky,Michael Konkel,Heidi Chen,Huailing Zhong,Mary W. Walker,Douglas A. Craig,Christophe P. G. Gerald,Theresa A. Branchek +13 more
TL;DR: Results indicate that Gal(3)-selective antagonists produce anxiolytic- and antidepressant-like effects, possibly by attenuating the inhibitory influence of galanin on 5-HT transmission at the level of the dorsal raphe nucleus.
Journal ArticleDOI
Activation of Delta Opioid Receptors Induces Receptor Insertion and Neuropeptide Secretion
Lan Bao,Shan-Xue Jin,Chen Zhang,Li-Hua Wang,Zhen-Zhong Xu,Fang-Xiong Zhang,Lie-Chen Wang,Feng-Shou Ning,Haijiang Cai,Ji-Song Guan,Hua-Sheng Xiao,Zhi-Qing David Xu,Cheng He,Tomas Hökfelt,Zhuan Zhou,Xu Zhang +15 more
TL;DR: DOR activation induces a Ca(2+)-dependent insertion of DORs that is coupled to a release of excitatory neuropeptides, suggesting that treatment of inflammatory pain should include blockade of D ORs.
Journal ArticleDOI
Chemical neuroanatomy of the dorsal raphe nucleus and adjacent structures of the mouse brain.
Wenyu Fu,Erwan Le Maître,Véronique Fabre,Jean-François Bernard,Zhi-Qing David Xu,Zhi-Qing David Xu,Tomas Hökfelt +6 more
TL;DR: The apparently low numbers of coexisting messengers in mouse serotonin neurons, compared to rat, indicate considerable species differences with regard to the chemical neuronatomy of the DRN, and extrapolation of DRN physiology, and possibly pathology, from rat to mouse, and even human, should be made with caution.