K
Kristina Warton
Researcher at University of New South Wales
Publications - 31
Citations - 1634
Kristina Warton is an academic researcher from University of New South Wales. The author has contributed to research in topics: Medicine & Ion channel. The author has an hindex of 14, co-authored 24 publications receiving 1435 citations. Previous affiliations of Kristina Warton include Garvan Institute of Medical Research.
Papers
More filters
Journal ArticleDOI
Crystal structure of a soluble form of the intracellular chloride ion channel CLIC1 (NCC27) at 1.4-A resolution.
Stephen J. Harrop,Matthew Z. DeMaere,W.D. Fairlie,T. Reztsova,Stella M. Valenzuela,Michele Mazzanti,Raffaella Tonini,Min Ru Qiu,Lucy Jankova,Kristina Warton,Asne R. Bauskin,W.M. Wu,S. Pankhurst,Terence J. Campbell,Samuel N. Breit,Paul M. G. Curmi +15 more
TL;DR: The structure indicates that CLIC1 is likely to be controlled by redox-dependent processes.
Journal ArticleDOI
Molecular Cloning and Expression of a Chloride Ion Channel of Cell Nuclei
Stella M. Valenzuela,Donald K. Martin,S B Por,Joan M. Robbins,Kristina Warton,Michelle Bootcov,Peter R. Schofield,Terence J. Campbell,Samuel N. Breit +8 more
TL;DR: The molecular cloning and characterization of a nuclear ion channel protein, designated nuclear chloride channel-27 (NCC27), from the human myelomonocytic cell line, U937, is described, which represents the first human member of a new class of organellar chloride ion channel proteins.
Journal ArticleDOI
Methylation of cell-free circulating DNA in the diagnosis of cancer
Kristina Warton,Goli Samimi +1 more
TL;DR: There are a number of potential circDNA biomarkers currently under investigation, and experience with SEPT9 shows that the time to clinical translation can be relatively rapid, supporting the promise of circDNA as a biomarker.
Journal ArticleDOI
The nuclear chloride ion channel NCC27 is involved in regulation of the cell cycle.
Stella M. Valenzuela,Michele Mazzanti,Raffaella Tonini,Min Ru Qiu,Kristina Warton,Elizabeth A. Musgrove,Terence J. Campbell,Samuel N. Breit +7 more
TL;DR: It is demonstrated that Cl− ion channel blockers known to block NCC27 led to arrest of CHO‐K1 cells in the G2/M stage of the cell cycle, the same stage at which this ion channel is selectively expressed on the plasma membrane.
Journal ArticleDOI
Methylated circulating tumor DNA in blood: power in cancer prognosis and response
TL;DR: A review of ctDNA methylation in the context of monitoring disease status, treatment response and determining the prognosis of cancer patients finds it amenable to the design of widely applicable clinical assays.