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Ksenija Jeftinija

Researcher at Iowa State University

Publications -  26
Citations -  5171

Ksenija Jeftinija is an academic researcher from Iowa State University. The author has contributed to research in topics: Glutamate receptor & Growth hormone secretion. The author has an hindex of 17, co-authored 26 publications receiving 4990 citations.

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Glutamate-mediated astrocyte-neuron signalling.

TL;DR: Astrocytes regulate neuronal calcium levels through the calcium-dependent release of glutamate, and an NMDA (N-methyl-d-aspartate) receptor-mediated increase in neuronal calcium is demonstrated.
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A mesoporous silica nanosphere-based carrier system with chemically removable CdS nanoparticle caps for stimuli-responsive controlled release of neurotransmitters and drug molecules.

TL;DR: An MCM-41 type mesoporous silica nanosphere-based controlled-release delivery system has been synthesized and characterized using surface-derivatized cadmium sulfide nanocrystals as chemically removable caps to encapsulate several pharmaceutical drug molecules and neurotransmitters inside the organically functionalized MSN Mesoporous framework.
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A polyamidoamine dendrimer-capped mesoporous silica nanosphere-based gene transfection reagent.

TL;DR: The G2-PAMAM-capped MSN material (G2-MSN) was used to complex with a plasmid DNA (pEGFP-C1) that encodes for an enhanced green fluorescence protein that renders the possibility to serve as a universal transmembrane carrier for intracellular drug delivery and imaging applications.
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ATP stimulates calcium-dependent glutamate release from cultured astrocytes.

TL;DR: The results suggest that ATP stimulates excitatory amino acid release from astrocytes via a calcium‐dependent anion‐transport sensitive mechanism.
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Structure and dynamics of the fusion pores in live GH-secreting cells revealed using atomic force microscopy.

TL;DR: The presence of pits and pits containing 100-200 nm in diameter depressions or fusion pores and their involvement in secretions in a neuroendocrine cell are documents for the first time.