Kuan Der Lee

TL;DR: Surprisingly, these cells were also able to differentiate into neuroglial- and hepatocyte-like cells under appropriate induction conditions and, thus, they may be more than mesenchymal stem cells as evidenced by their ability to differentiation into cell types of all 3 germ layers.

TL;DR: Human MSCs from different sources are able to differentiate into functional hepatocyte‐like cells and, hence, may serve as a cell source for tissue engineering and cell therapy of hepatic tissues and indicates that a revision of the definition may be required.

TL;DR: A targeted chromosomal breakpoint sequencing method was developed for searching the ROS1 fusion gene and was compared with fluorescence in situ hybridization, immunohistochemistry, RT-qPCR using 260 lung cancer samples of Southern Taiwan, showing that ROS1-altered cases were present at low frequencies, did not share distinct clinicopathological features, and often carried other driver mutations.

TL;DR: The authors compared the therapeutic efficacy, mechanisms, and immune response of human mesenchymal stem cells (MSC) and mouse MSCs (mMSCs) in immunocompetent mice with CCl4-induced acute liver failure.

TL;DR: In this paper , the authors examined the functions of endogenous chemokine ligand 2 (CCL2) of mesenchymal stem cells (MSCs) in cancer biology and found that CCL2 KO MSCs showed anti-tumor function when injected with prostate cancer cells into mice.