K
Kwang Hee Son
Researcher at Korea Research Institute of Bioscience and Biotechnology
Publications - 49
Citations - 1016
Kwang Hee Son is an academic researcher from Korea Research Institute of Bioscience and Biotechnology. The author has contributed to research in topics: Biology & Medicine. The author has an hindex of 16, co-authored 41 publications receiving 948 citations. Previous affiliations of Kwang Hee Son include Korea Institute of Science and Technology.
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Journal ArticleDOI
Blocking tumor cell migration and invasion with biphenyl isoxazole derivative KRIBB3, a synthetic molecule that inhibits Hsp27 phosphorylation.
Ki Deok Shin,Mi-Young Lee,Dae Seop Shin,Sangku Lee,Kwang Hee Son,Sukhoon Koh,Young Ki Paik,Byoung Mog Kwon,Dong Cho Han +8 more
TL;DR: Overall, the results demonstrate that KRIBB3 inhibits tumor cell migration and invasion by blocking protein kinase C-dependent phosphorylation of Hsp27 through its direct binding to HSP27.
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T-cell specific immunosuppression by prodigiosin isolated from Serratia marcescens.
Sang Bae Han,Hwan Mook Kim,Young-Hee Kim,Chang Woo Lee,Eun-Sook Jang,Kwang Hee Son,Sung Uk Kim,Young-Kook Kim +7 more
TL;DR: Prodigiosin was isolated from the culture broth of Serratia marcescens B-1231 and did not cause death in vitro to lymphocytes at effective concentrations and also did not show toxicity in vivo to lymphoid organs at effective dosages.
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2′-Benzoyloxycinnamaldehyde Induces Apoptosis in Human Carcinoma via Reactive Oxygen Species
Dong Cho Han,Mi-Young Lee,Ki Deok Shin,Sun Bok Jeon,Jung Min Kim,Kwang Hee Son,Hyoung Chin Kim,Hwan Mook Kim,Byoung Mog Kwon +8 more
TL;DR: Results suggest that BCA is a good drug candidate for cancer therapy and suggest that reactive oxygen species are major regulator of BCA-induced apoptosis.
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Anti-tumor abietane diterpenes from the cones of Sequoia sempervirens.
TL;DR: A new abietane, namely, 20-hydroxyferruginol was isolated from the cones of Sequoia sempervirens and strongly inhibited colon, lung, and breast human tumors and oncogene transformed cells with GI 2-5 microg/mL.
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Antitumor activity of flavones isolated from Artemisia argyi
Jeong-Min Seo,Hyun Mi Kang,Kwang Hee Son,Jong Han Kim,Changwoo Lee,Hwan Mook Kim,Soo-Ik Chang,Byoung-Mog Kwon +7 more
TL;DR: These flavones inhibited farnesyl protein transferase with IC 50 values of 25 - 200 microg/mL and inhibited proliferation of a couple of tumor cell lines and also inhibited neovascularization in a chick chorioallantoic membrane assay.